| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Outline of Final Research Achievements |
This study evaluated the effect of two desensitizers on inhibition of dentin demineralization, after immersion in artificial saliva using micro-computed tomography (micro-CT).
Dentin blocks cut from bovine incisors were treated with deionized water (DW) or a fluoride varnish (DP), a calcium phosphate desensitizer (TMD), and a fluoro-alumino-calcium silicate-based desensitizer (NS). After each treatment, the specimens were pre-immersed in artificial saliva (pH 6.5) for either 1 d or 1 wk. The mineral loss of the specimens after demineralization (pH 5.0, 3 h) was evaluated by micro-CT. DP was the most effective treatment against demineralization, followed by NS. NS showed significantly better reduction in mineral loss following immersion for 1 wk in artificial saliva than for 1 d.
The application of TMD and NS to the exposed dentin surface resulted in inhibition of demineralization, with NS resulting in improved inhibition after prolonged immersion in artificial saliva.
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