Multiphasic analyses on factors associated with the effective use of public-access automated external defibrillations (AEDs) as well as the quality of cardiopulmonary resuscitation (CPR)

• Project/Area Number: 25870391
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Epidemiology and preventive medicine; Emergency medicine
• Research Institution: Osaka University
• Principal Investigator: Kitamura Tetsuhisa 大阪大学, 医学(系)研究科(研究院), 助教 (30639810)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000); Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
• Keywords: 蘇生科学 / 循環器学 / 疫学 / 救急医学 / 病院外心停止 / 臨床疫学

Outline of Final Research Achievements

The aim of this study conducted multiphasic analyses on factors associated with the effective use of public-access automated external defibrillations (AEDs) as well as the quality of cardiopulmonary resuscitation (CPR). We collected approximately 56000 OHCA patients in Osaka Prefecture, Japan between 2005 and 2012. Public-access AED pads were applied to 3.5% of OHCA patients (351/9978) between 2011 and 2012. Arrests in public places, witness by bystanders, and bystander-initiated CPR were significantly associated with high proportion of public-access AED pad application. Between 2005 and 2012, the chest compression-only CPR (CCCPR) instruction group received bystander CPR more frequently than conventional CPR instruction group (70.0% versus 62.1%, p<0.001). In the multivariable analysis, CCCPR dispatcher instruction was significantly associated with provision of bystander CPR compared with conventional CPR instruction (adjusted odds ratio 1.44, 95% CI 1.34-1.55).

Research Products

• [Journal Article] Temporal trends in outcomes after out-of-hospital cardiac arrests witnessed by emergency medical services in Japan: a population-based study (2016)
  • Author(s): Kajino K, Kitamura T, Kiyohara K, Iwami T, Daya M, Ong MHE, Shimazu T, Sadamitsu D
  • Journal Title: Prehospital Emergency Care Volume: E-pub ahead of print Issue: 4 Pages: 477-484
  • DOI: 10.3109/10903127.2015.1115931
  • Peer Reviewed
• [Journal Article] Epidemiology of out-of-hospital cardiac arrests among Japanese centenarians: 2005-2013 (2016)
  • Author(s): Kitamura T, Kiyohara K, Matsuyama T, Izawa J, Shimamoto T, Hatakeyama T, Fujii T, Nishiyama C, Iwami T
  • Journal Title: The American Journal of Cardiology Volume: 117 Issue: 6 Pages: 894-900
  • DOI: 10.1016/j.amjcard.2015.12.042
  • Peer Reviewed
• [Journal Article] Is Survival After Out-of-Hospital Cardiac Arrests Worse During Days of National Academic Meetings in Japan? A Population-Based Study (2016)
  • Author(s): Kitamura T, Kiyohara K, Matsuyama T, Hatakeyama T, Shimamoto T, Izawa J, Nishiyama C, Iwami T
  • Journal Title: Journal of Epidemiology Volume: 26 Issue: 3 Pages: 155-162
  • DOI: 10.2188/jea.JE20150100
  • NAID: 130005131968
  • ISSN: 0917-5040, 1349-9092
  • Peer Reviewed / Open Access
• [Journal Article] Compression-only CPR training in elementary schools and students’ attitude toward CPR. (2015)
  • Author(s): Kitamura T, Nishiyama C, Murakami Y, Yonezawa T, Nakai S, Hamanishi M, Marukawa S, Sakamoto T, Iwami T.
  • Journal Title: Pediatrics International Volume: 未定 Issue: 8 Pages: 698-704
  • DOI: 10.1111/ped.12881
  • Peer Reviewed
• [Journal Article] Dispatcher instruction of chest compression-only CPR increases actual provision of bystander CPR (2015)
  • Author(s): Shimamoto T, Iwami T, Kitamura T, Nishiyama C, Sakai T, Nishiuchi T, Hayashi Y, Kawamura T; Utstein Osaka Project.
  • Journal Title: Resuscitation Volume: 96 Pages: 9-15
  • DOI: 10.1016/j.resuscitation.2015.07.009
  • Peer Reviewed
• [Journal Article] Temporal trends in out-of-hospital cardiac arrest survival outcomes between two metropolitan communities: Seoul-Osaka Resuscitation Study (2015)
  • Author(s): Ro YS, Shin SD, Kitamura T, Lee EJ, Kajino K, Song KJ, Nishiyama C, Kong SY, Sakai T, Nishiuchi T, Hayashi Y, Iwami T
  • Journal Title: BMJ Open Volume: 5 Issue: 6 Pages: e007626-e007626
  • DOI: 10.1136/bmjopen-2015-007626
  • NAID: 120005674597
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Dissemination of chest compression-only cardiopulmonary resuscitation and survival after out-of-hospital cardiac arrest (2015)
  • Author(s): Iwami T,* Kitamura T,* Kiyohara K,* Kawamura T
  • Journal Title: Circulation Volume: 132 Issue: 5 Pages: 415-422
  • DOI: 10.1161/circulationaha.114.014905
  • Peer Reviewed
• [Journal Article] Different Impacts of Time From Collapse to First Cardiopulmonary Resuscitation on Outcomes After Witnessed Out-of-Hospital Cardiac Arrest in Adults (2015)
  • Author(s): Masahiko Hara, Kenichi Hayashi, SHungo Hikoso, Yasushi Sakata, Tetsuhisa Kitamura
  • Journal Title: Circulation: Cardiovascular Quality and Outcomes Volume: 未定 Issue: 3 Pages: 277-284
  • DOI: 10.1161/circoutcomes.115.001864
  • Peer Reviewed
• [Journal Article] Effectiveness of simplified 15-min refresher CPR training program: a randomized controlled trial (2015)
  • Author(s): Nishiyama C, Iwami T, Murakami Y, Kitamura T, Okamoto Y, Marukawa S, Sakamoto T, Kawamura T
  • Journal Title: Resuscitation Volume: 90(5) Pages: 56-60
  • DOI: 10.1016/j.resuscitation.2015.02.015
  • Peer Reviewed
• [Journal Article] Cardiopulmonary Resuscitation Support Application on a Smartphone – Randomized Controlled Trial – (2015)
  • Author(s): Sakai T, Kitamura T, Nishiyama C, Murakami Y, Ando M, KawamuraT, Tasaki O, Kuwagata Y, Shimazu T, Iwami T
  • Journal Title: Circulation Journal Volume: 79 Issue: 5 Pages: 1052-1057
  • DOI: 10.1253/circj.CJ-14-1258
  • NAID: 130005066260
  • ISSN: 1346-9843, 1347-4820
  • Peer Reviewed
• [Journal Article] Epidemiology and outcome of adult out-of-hospital cardiac arrest with non-cardiac origin in Osaka: a population-based study (2014)
  • Author(s): Kitamura T, Kiyohara K, Sakai T, Iwami T, Nishiyama C, Kajino K, Nishiuchi T, Hayashi Y, Katayama Y, Yoshiya K, Shimazu T
  • Journal Title: BMJ Open Volume: 4(12) Issue: 12 Pages: e006462-e006462
  • DOI: 10.1136/bmjopen-2014-006462
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Impact of the Great East Japan Earthquake on out-of-hospital cardiac arrest with cardiac origin in non-disaster areas (2014)
  • Author(s): Kiyohara K, Kitamura T, Iwami T, Nishiyama C, Kawamura T
  • Journal Title: Journal of Epidemiology and Community Health Volume: 69(2) Issue: 2 Pages: 185-188
  • DOI: 10.1136/jech-2014-204380
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Survival following witnessed pediatric out-of-hospital cardiac arrests during nights and weekends (2014)
  • Author(s): Kitamura T, Kiyohara K, Nitta M, Nadkarni VM, Berg RA, Iwami T
  • Journal Title: Resuscitation Volume: 85(12) Issue: 12 Pages: 1692-1698
  • DOI: 10.1016/j.resuscitation.2014.08.035
  • Peer Reviewed
• [Journal Article] Effectiveness of prehospital Magill forceps use for out-of-hospital cardiac arrest due to foreign body airway obstruction in Osaka City. (2014)
  • Author(s): Sakai T, Kitamura T, Shiozaki T, et al
  • Journal Title: Scand J Trauma Resusc Emerg Med Volume: 22 Issue: 1 Pages: 53-59
  • DOI: 10.1186/s13049-014-0053-3
  • NAID: 120006955480
  • Peer Reviewed / Open Access
• [Journal Article] Trends in survival among elderly patients with out-of-hospital cardiac arrest: a prospective, population-based observation from 1999 to 2011 in Osaka (2014)
  • Author(s): Kitamura T, Morita S, Kiyohara K, Nishiyama C, Kajino K, Sakai T, Nishiuchi T, Hayashi Y, Shimazu T, Iwami T
  • Journal Title: Resuscitation Volume: 85(11) Issue: 11 Pages: 1432-1438
  • DOI: 10.1016/j.resuscitation.2014.07.017
  • Peer Reviewed
• [Journal Article] Epidemiological characteristics of sudden cardiac arrest in schools. (2014)
  • Author(s): Nishiuchi T., Hayashino Y., Iwami T., Kitamura T., Nishiyama C., Kajino K., Nitta M., Hayashi Y., Hiraide A., Utstein Osaka Project Investigators.
  • Journal Title: Resuscitation Volume: 85 Issue: 8 Pages: 1001-6
  • DOI: 10.1016/j.resuscitation.2014.04.027
  • Peer Reviewed
• [Journal Article] Outcomes of out-of-hospital cardiac arrest by public location in the public-access defibrillation era (2014)
  • Author(s): Murakami Y, Iwami T, Kitamura T, Nishiyama C, Nishiuchi T, Hayashi Y, Kawamura T
  • Journal Title: Journal of the American Heart Association Volume: 3(2) Issue: 2
  • DOI: 10.1161/jaha.113.000533
  • NAID: 120006955479
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Actual treatments for out-of-hospital ventricular fibrillation at critical care medical centers in Osaka: a pilot descriptive study (2014)
  • Author(s): Sakai T, Kitamura T, Iwami T, Hayashi Y, Rinka H, Ohishi Y, Mohri T, Kishimoto M, Kawaguchi R, Kajino K, Yumoto T, Uejima T, Nitta M, Nishiuchi T, Shiokawa C, Irisawa T, Tasaki O, Ogura H, Kuwagata Y, Shimazu T
  • Journal Title: Acute Medicine & Surgery Volume: E-pub ahead of print Issue: 3 Pages: 150-158
  • DOI: 10.1002/ams2.27
  • Peer Reviewed
• [Journal Article] Amburance calls and prehospital transportation time of emergency patients with cardiovascular events in Osaka City. (2014)
  • Author(s): Kitamura T, Iwami T, Kawamura T, Nishiyama C, Sakai T, Tanigawa K, Sasaki M, Kajino K, Irusawa T, Hayashida S, Nishiuchi T, Hiraide A.
  • Journal Title: Acute medicine & Surgery Volume: 5 MAR Issue: 3 Pages: 1-10
  • DOI: 10.1002/ams2.25
  • Peer Reviewed
• [Journal Article] Long-term retention of CPR skills after shortened chest compression-only CPR training and conventional CPR training: a randomized controlled trial (2014)
  • Author(s): Nishiyama C, Iwami T, Kitamura T, Ando M, Sakamoto T, Marukawa S, Kawamura T
  • Journal Title: Academic Emergency Medicine Volume: 21(1) Issue: 1 Pages: 47-54
  • DOI: 10.1111/acem.12293
  • Peer Reviewed
• [Journal Article] An association between systolic blood pressure and stroke among patients with impaired consciousness in out-of-hospital emergency settings. (2014)
  • Author(s): Irisawa T, Iwami T, Kitamura T, Nishiyama C, Sakai T, Tanigawa-Sugihara K, Hayashida S, Nishiuchi T, Shiozaki T, Tasaki O, Kawamura T, Hiraide A, Shimazu T
  • Journal Title: BMC Emerg Med Volume: 13 Issue: 1 Pages: 24-31
  • DOI: 10.1186/1471-227x-13-24
  • NAID: 120006986795
  • Peer Reviewed
• [Journal Article] Association between resuscitation time interval at the scene and neurological outcome after out-of-hospital cardiac arrest in two Asian cities (2014)
  • Author(s): Shin SD, Kitamura T, Hwang SS, Kajino K, Song KJ, Ro YS, Nishiuchi T, Iwami T
  • Journal Title: Resuscitation Volume: 85(2) Issue: 2 Pages: 203-210
  • DOI: 10.1016/j.resuscitation.2013.10.021
  • NAID: 120005373228
  • Peer Reviewed
• [Journal Article] Impact of the number of on-scene emergency life-saving technicians and outcomes from out-of-hospital cardiac arrest in Osaka City (2014)
  • Author(s): Kajino K, Kitamura T, Iwami T, Daya M, Ong ME, Nishiyama C, Sakai T, Tanigawa-Sugihara K, Hayashida S, Nishiuchi T, Hayashi Y, Hiraide A, Shimazu T
  • Journal Title: Resuscitation Volume: 85(1) Issue: 11 Pages: 59-64
  • DOI: 10.1016/j.resuscitation.2013.06.017
  • Peer Reviewed
• [Journal Article] The Great East Japan Earthquake and out-of-hospital cardiac arrest (2013)
  • Author(s): Kitamura T, Kiyohara K, Iwami T
  • Journal Title: The New England Journal of Medicine Volume: 369(22) Issue: 22 Pages: 2165-2167
  • DOI: 10.1056/nejmc1306058
  • NAID: 120006955474
  • Peer Reviewed
• [Journal Article] Regional Variation in Survival Following Pediatric Out-of-Hospital Cardiac Arrest (2013)
  • Author(s): Okamoto Y, Iwami T, Kitamura T, Nitta M, Hiraide A, Morishima T, Kawamura T
  • Journal Title: Circulation Journal Volume: 77 Issue: 10 Pages: 2596-2603
  • DOI: 10.1253/circj.CJ-12-1604
  • NAID: 10031191801
  • ISSN: 1346-9843, 1347-4820
  • Peer Reviewed
• [Journal Article] Association Between Atmospheric Conditions and Occurrence of Out-of-Hospital Cardiac Arrest (2013)
  • Author(s): Tanigawa-Sugihara K, Iwami T, Nishiyama C, Kitamura T, Goto M, Ando M, Nishiuchi T, Hayashi Y, Kawamura T
  • Journal Title: Circulation Journal Volume: 77 Issue: 8 Pages: 2073-2078
  • DOI: 10.1253/circj.CJ-13-0076
  • NAID: 10031178678
  • ISSN: 1346-9843, 1347-4820
  • Peer Reviewed
• [Presentation] Different Outcomes by first documented rhythm after witnessed out-of-hospital cardiac arrest in children (2015)
  • Author(s): Hara M, Hayashi K, Kitamura T
  • Organizer: 2015 American Heart Association Scientific Session
  • Place of Presentation: Orland, Fla, USA
  • Year and Date: 2015-11-07
  • Int'l Joint Research
• [Presentation] Effectiveness of a New Smartphone Application “AED-SOS” to Call Co-rescuers Carrying an AED for Cardiac Arrests: A Randomized Controlled Trial (2015)
  • Author(s): Hatakeyama T, Nishiyama C, Kitamura T, Matsuyama T, Izawa J, Kawamura T, Iwami T
  • Organizer: 2015 American Heart Association Scientific Session
  • Place of Presentation: Orland, Fla, USA
  • Year and Date: 2015-11-07
  • Int'l Joint Research
• [Presentation] Application of public-access AED pads for patients with out-of-hospital cardiac arrests in Osaka City (2015)
  • Author(s): Kosuke Kiyohara, Tetsuhisa Kitamura, Tomohiko Sakai, Taku Iwami
  • Organizer: 第25回日本疫学会
  • Place of Presentation: 名古屋
  • Year and Date: 2015-01-21 – 2015-01-23
• [Presentation] Wider Dissemination of CPR Training with Chest Compression-only CPR and Changes in Bystander CPR in a Community (2014)
  • Author(s): Iwami T, Kitamura T, Nishiyama C, Shimamoto T, Kawamura T, Marukawa S, Sakamoto T
  • Organizer: 2014 American Heart Association Scientific Sessions
  • Place of Presentation: Chicago, Illinois, United States
  • Year and Date: 2014-11-15 – 2014-11-19
• [Presentation] Effectiveness of Refresher Self-Training of Chest Compression--Only Cardiopulmonary Resuscitation: A Randomized Controlled Trial (2014)
  • Author(s): Shimamoto T, Nishiyama C, Kawamura T, Kiyohara K, Kitamura T, Sakamoto T, Iwami T
  • Organizer: 2014 American Heart Association Scientific Sessions
  • Place of Presentation: Chicago, Illinois, United States
  • Year and Date: 2014-11-15 – 2014-11-19
• [Presentation] Quality of Cardiopulmonary Resuscitation by Bystanders and Survival After Out-of-Hospital Cardiac Arrest (2014)
  • Author(s): Nishiyama C, Kitamura T, Shimamoto T, Kawamura T, Sakamoto T, Iwami T
  • Organizer: 2014 American Heart Association Scientific Sessions
  • Place of Presentation: Chicago, Illinois, United States
  • Year and Date: 2014-11-15 – 2014-11-19
• [Presentation] 全国ウツタイン統計における救急隊目撃症例の経年変化について (2014)
  • Author(s): 梶野健太郎、北村哲久、石見拓、嶋津岳士、定光大海
  • Organizer: 第42回日本救急医学会総会
  • Place of Presentation: 福岡
  • Year and Date: 2014-10-28 – 2014-11-30
• [Presentation] 高齢者院外心停止後の生存についての経年変化～大阪ウツタインプロジェクト：1999－2011年の10876症例の検討～ (2014)
  • Author(s): 森田幸子、北村哲久、清原康介、石見拓、西山知佳、西内辰也、林靖之、甲斐達郎
  • Organizer: 第42回日本救急医学会総会
  • Place of Presentation: 福岡
  • Year and Date: 2014-10-28 – 2014-11-30
• [Presentation] ウツタインデータから見えた心肺蘇生法
  • Author(s): 北村哲久
  • Organizer: 日本集中治療学会
  • Place of Presentation: 京都国際会館
  • Invited
• [Remarks] 心肺脳蘇生研究グループ CCresus
  • URL: http://cc-resus.com/