Expression of photoreceptor protein on the melanocyte

Research Project

Project/Area Number	25870427
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Multi-year Fund
Research Field	Plastic surgery Dermatology
Research Institution	Kobe University
Principal Investigator	Fujii Miki 神戸大学, 医学(系)研究科(研究院), 研究員 (80444602)
Project Period (FY)	2013-04-01 – 2016-03-31
Project Status	Completed (Fiscal Year 2015)
Budget Amount *help	¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000) Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000) Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000) Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords	メラノサイト / 光受容 / メラノプシン / Gnaq / Melanopsin / melanopsin
Outline of Final Research Achievements	Expression of OPN4 variant 1 from a skin tissue and a cultured cell was confirmed. Furthermore, we confirmed new variant (variant 3) with 41bp of insertion. The insertion was recognized between exon3 and exon4, and it was suspected that this was new variant which occurred during splicing. Coexpression of OPN4 and Gnaq was confirmed in cultured melanocyte with western blotting and histology.

Report

(4 results)