Therapeutic effect of cell transplantation with novel induced neural stem cells in stroke animal model
Project/Area Number |
25870460
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Neurosurgery
General medical chemistry
|
Research Institution | Okayama University |
Principal Investigator |
Yamashita Toru 岡山大学, 医歯(薬)学総合研究科, 講師 (60644408)
|
Project Period (FY) |
2013-04-01 – 2016-03-31
|
Project Status |
Completed (Fiscal Year 2015)
|
Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
|
Keywords | 脳梗塞 / 細胞移植 / iN細胞 / iPS細胞 / ダイレクトリプログラミング / ダイレクトリプログラミング / iNS細胞 |
Outline of Final Research Achievements |
iNSC transplantation successfully improved the survival rate of stroke model mice with significant functional recovery from the stroke, suggesting that the directly converted iNSCs may represent a promising and safe cell resource for transplantation therapy in patients suffering from ischemic stroke.
|
Report
(4 results)
Research Products
(14 results)