| Project/Area Number |
25870592
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Psychiatric science
Basic / Social brain science
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| Research Institution | Tokyo Metropolitan University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
JINBO Daiki 昭和大学, 医学部, 兼任講師 (60601317)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2013: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 脳機能イメージング / 統合失調症 / 自閉スペクトラム症 / セルフ / fMRI / 自己 / 自閉症 |
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| Outline of Final Research Achievements |
The project conducted a series of fMRI experiments to examine functional alterations of neural substrates for self-related representation in autism spectrum disorders (ASD) and schizophrenia. In the ASD study, we examined functional connectivity during the resting-state and evaluation of self and other people. In the schizophrenia study, we examined relationship between the resting-state activity and auditory verbal hallucinations that are related to abnormalities of self-representations. The analyses revealed abnormalities in functional connectivity between brain regions in each of ASD and schizophrenia, indicating alterations of neural networks that may subserve self-related representations in these disorders.
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