• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Resilinece and its biologocal correlates in schizophrenia

Research Project

Project/Area Number 25870713
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field General internal medicine(including psychosomatic medicine)
Psychiatric science
Research InstitutionKeio University

Principal Investigator

UCHIDA Hiroyuki  慶應義塾大学, 医学部, 講師 (40327630)

Project Period (FY) 2013-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Keywords統合失調症 / レジリエンス / ストレス / 回復
Outline of Final Research Achievements

The present study, including 60 patients with schizophrenia, found the mean Resilience Scale total score of 110 and demonstrated that the degree of resilience was positively correlated with self-esteem, spirituality, and quality of life and negatively with hopelessness and internalized stigma. No association was observed between the degree of resilience and plasma brain derived neurotrophic factor (BDNF), adrenocorticotropic hormone (ACTH), cortisol, high-sensitivity C-reactive protein, or saliva amylase level. These findings suggest that intervention to enhance resilience levels by targeting the psychological aspects that were found to be associated with resilience could become a real clinical application. On the other hand, further investigations are warranted to elucidate biological basis underlying resilience.

Report

(3 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • Research Products

    (5 results)

All 2015 2014

All Presentation (5 results)

  • [Presentation] A systematic review of evidence on resilience research in schizophrenia and future directions2015

    • Author(s)
      Mizuno Y, Hofer A, Suzuki T, Mimura M, Fleischhacker W, Uchida H
    • Organizer
      15th International Congress on Schizophrenia Research
    • Place of Presentation
      Colorado Springs, United States
    • Year and Date
      2015-04-01
    • Related Report
      2014 Annual Research Report
  • [Presentation] 統合失調症および双極I型障害患者における自覚的レジリエンスと宗教性/スピリチュアリティ:横断研究2015

    • Author(s)
      水野裕也、Alex Hofer、鈴木健文、三村將、W. Wolfgang Fleischhacker、内田裕之
    • Organizer
      第34回日本社会精神医学会
    • Place of Presentation
      富山国際会議場(富山県富山市)
    • Year and Date
      2015-03-05
    • Related Report
      2014 Annual Research Report
  • [Presentation] Biological and clinical correlates of resilience in patients with schizophrenia: a cross-sectional study2014

    • Author(s)
      Mizuno Y, Hofer A, Fleischhacker WW, Uchida H
    • Organizer
      53rd American College of Neuropsychopharmacology Annual Meeting
    • Place of Presentation
      Phoenix, United States
    • Year and Date
      2014-12-10
    • Related Report
      2014 Annual Research Report
  • [Presentation] 統合失調症患者のレジリエンスと関連する生物学的・臨床的要因:横断研究2014

    • Author(s)
      水野裕也,鈴木健文,Alex Hofer,W. Wolfgang Fleischhacker,櫻井準,新福正機,藤井和人,三村將,内田裕之
    • Organizer
      第24回日本臨床精神神経薬理学会/第44回日本神経精神薬理学会合同年会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2014-11-20
    • Related Report
      2014 Annual Research Report
  • [Presentation] Clinical and biological correlates of resilience in patients with schizophrenia: A cross-sectional study2014

    • Author(s)
      Mizuno Y, Suzuki T, Hofer A. Fleischhacker WW, Uchida T, Yoshida K, Sakurai H, Watanabbe K, Mimura M, Uchida H
    • Organizer
      29th Collegium Internationale Neuro-Psychopharmacologium
    • Place of Presentation
      Vancouver, Canada
    • Year and Date
      2014-06-24
    • Related Report
      2014 Annual Research Report

URL: 

Published: 2014-07-25   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi