| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Outline of Final Research Achievements |
When unexpected environmental pollution is suspected, the pollutants are needed to be quickly identified for evaluating its environmental impacts. Organisms have an ability to adapt to environmental changes by adjusting the biological components. Lipids are one of the major biological components, and environmental changes or diseases have an influence on its composition. We examined whether LC-MSMS analyses can capture the specific change patterns of lipid composition response to a toxic material stresses. Detecting condition of the lipid components was studied as a sample the total lipid extracted from cyanobacteria, and it has been established that analysis method that can be separated and detected simultaneously approximately a hundred and several tens of components. Then, discovery of lipid biomarkers response to some heavy metals exposure is attempted, and some components were successfully found as lipid to increase or decrease more than twice.
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