| Project/Area Number |
25870862
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Periodontology
Pathobiological dentistry/Dental radiology
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| Research Institution | Aichi Gakuin University |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2016-03-31
|
| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2014: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Keywords | NIRS / test-retest reliability / 覚醒時ブラキシズム / 歯根膜 / 脳機能測定 / ブラキシズム |
|---|
| Outline of Final Research Achievements |
In order to develop a diagnostic method of awake bruxism (AB), we focused on the changes in the perception of the periodontal ligament. Our purpose of this study was to investigate whether the measurement of brain activity by near-infrared spectroscopy (NIRS) is applicable to diagnosis of AB. First, we verified the reproducibility of repeated measurements in brain activity (oxy-Hb) during clenching task. The results were confirmed to have a sufficient reproducibility for diagnostic purpose. In addition, the subjects were classified into two groups (AB and healthy) and clenching tasks were carried out to compare the cerebral blood flow dynamics between each group. The objective was to find the specific brain activity in the AB subjects. As a result, we observed a significant change of oxy-Hb in the part of the prefrontal cortex that shows high reproducibility. Measurement of brain activity using NIRS was suggested as a candidate of a diagnostic method of AB.
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