| Project/Area Number |
25871014
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Molecular biology
Genetics/Chromosome dynamics
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| Research Institution | Okinawa Institute of Science and Technology Graduate University |
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Principal Investigator |
SAZE Hidetoshi 沖縄科学技術大学院大学, その他の研究科, 准教授 (70510006)
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
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| Keywords | エピジェネティクスピジェネティクス / トランスポゾン / DNAメチル化 / 植物科学 / エピジェネティクス / シロイヌナズナ / ヒストンメチル化 |
|---|
| Outline of Final Research Achievements |
The genomes of vertebrates and plants contain a substantial number of transposable elements (TEs), which are silenced by repressive epigenetic modifications, such as cytosine methylation. Using Arabidopsis DNA hypermethylation mtants, we found that removal of H3K9 methylation and non-CG methylation at transcribed genic regions is affected by epigenetic regulation of H3K9 demethylase gene.
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