Identification of novel tyrosine kinase fusion genes in colorectal cancer
| Project/Area Number |
25871072
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Gastroenterology
Experimental pathology
|
|---|
| Research Institution | Japanese Foundation for Cancer Research |
|---|
Principal Investigator |
SAKATA Seiji 公益財団法人がん研究会, 分子標的病理プロジェクト, 研究員 (00617433)
|
|---|
| Project Period (FY) |
2013-04-01 – 2015-03-31
|
| Project Status |
Completed (Fiscal Year 2014)
|
| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
|
|---|
| Keywords | チロシンキナーゼ / 融合遺伝子 |
|---|
| Outline of Final Research Achievements |
We found several novel tyrosine kinase fusion genes in colorectal cancer using a histopathology-based screening system. We analyzed clinicopathological data and other gene mutations in colorectal cancers with the identified fusion genes. We are investigating tumorigenicity and drug sensitivity of the identified fusion genes.
|
Report
(3 results)
Research Products
(4 results)
