Development of monitoring method of irradiation depth in body by measuring low energy photons for heavy ion therapy

• Project/Area Number: 25871094
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Medical systems; Biomedical engineering/Biomaterial science and engineering
• Research Institution: Japan Atomic Energy Agency
• Principal Investigator: YAMAGUCHI Mitsutaka 独立行政法人日本原子力研究開発機構, 原子力科学研究部門 高崎量子応用研究所 放射線高度利用施設部, 研究員 (10375404)
• Project Period (FY): 2013-04-01 – 2015-03-31
• Project Status: Completed (Fiscal Year 2014)
• Budget Amount: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000); Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000); Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
• Keywords: ビームモニタリング / 粒子線治療 / 二次電子 / 制動輻射 / モンテカルロシミュレーション

Outline of Final Research Achievements

Realtime monitoring methods of irradiated ions are important techniques to improve reliability of particle therapies. The purpose of this research is to develop an estimation method of particle range position by measuring low energy photons. Firstly, by a result of a Monte Carlo simulation, it was found that emitting particles from irradiated target consist of the secondary electron bremsstrahlung. Based on this result, an experiment was performed by using a prototype machine of realtime monitoring. By the experiment, it was found that the elimination of a background component which consist of scattered photons is essential for the realization of this monitoring method and the elimination is able to be done by optimizing the thickness of a detector.

Research Products

• [Presentation] An Experimental Test of a Beam Monitoring Method by Measuring Low Energy Photons Using a Gamma Camera (2014)
  • Author(s): Mitsutaka Yamaguchi, Yuto Nagao, Yuichi Saito, Naoki Kawachi, Shu Fujimaki, Seiichi Yamamoto, Masataka Komori, Toshiyuki Toshito
  • Organizer: 2014 IEEE Nuclear Science Symposium & Medical Imaging Conference
  • Place of Presentation: ワシントン州立コンベンションセンター （アメリカ合衆国 ワシントン州 シアトル）
  • Year and Date: 2014-11-08 – 2014-11-15
• [Presentation] 医学・生物学用マルチヘッド Si/CdTe 半導体コンプトンカメラのための横断断層撮像画質の シミュレーションによる評価 (2014)
  • Author(s): 山口 充孝、酒井 真理、長尾 悠人、河地 有木、藤巻 秀、荒川 和夫、神谷 富裕、小高 裕和、国分 紀秀、武田 伸一郎、渡辺 伸、高橋 忠幸、鳥飼 幸太、中野 隆史
  • Organizer: 第61回応用物理学会春季学術講演会
  • Place of Presentation: 青山学院大学相模原キャンパス
• [Presentation] A new method for monitoring beam range by measuring low energy photons (2013)
  • Author(s): Mitsutaka Yamaguchi, Kota Torikai, Naoki Kawachi, Hirofumi Shimada, Takahiro Satoh, Yuto Nagao, Shu Fujimaki, Motohide Kokubun, Shin Watanabe, Tadayuki Takahashi, Kazuo Arakawa, Tomihiro Kamiya, Takashi Nakano
  • Organizer: 2013 IEEE Nuclear Science Symposium & Medical Imaging Conference
  • Place of Presentation: COEX, Seoul (Korea)