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Elucidation of the mechanism of increased mammary vitamin E transfer that induces hypovitaminosis E: with the aim of reducing the risk of peripartum disease on dairy cow

Research Project

Project/Area Number 25871102
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Veterinary medical science
Animal production science
Research InstitutionNational Agriculture and Food Research Organization

Principal Investigator

HAGA Satoshi  独立行政法人農業・食品産業技術総合研究機構, 畜産草地研究所草地管理研究領域, 研究員 (90442748)

Research Collaborator KATOH Kazuo  
ISHIZAKI Hiroshi  
Project Period (FY) 2013-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2013: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywordsウシ乳腺上皮細胞 / ビタミンE / 周産期疾病 / 初乳 / 乳腺バイオプシー
Outline of Final Research Achievements

In dairy cows, the majority of the production diseases occur around calving or during early lactation. The management of dairy farm is made worse by the many treatment pay and loss. This might be caused by the deficiency of vitamin E that very important nutrient can affect the immune and metabolic functions. The aim of this study was to elucidate the mechanism of the deficiency of vitamin E in dairy cows during transition period. In fact, we made clear the expression property of vitamin E-related gene in bovine mammary gland and mammary epithelial cells. The results of this study could help in the developmental work to reduce the risk of the deficiency of vitamin E and production diseases in dairy cows.

Report

(3 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • Research Products

    (3 results)

All 2014 2013

All Presentation (3 results)

  • [Presentation] Tissues distribution and expression changes of the α-tocopherol related genes due to short term high dose oral administration of α-tocopherol in weaned beef calve2014

    • Author(s)
      芳賀聡、中野美和、石崎宏、盧尚建、加藤和雄
    • Organizer
      Joint ISNH/ISRP International conference
    • Place of Presentation
      オーストラリア キャンベラ ナショナルコンベンションセンター
    • Year and Date
      2014-09-08 – 2014-09-12
    • Related Report
      2014 Annual Research Report
  • [Presentation] ウシ乳腺上皮細胞におけるαトコフェロール細胞内輸送関連分子の発現に及ぼす催乳性ホルモンの影響2014

    • Author(s)
      芳賀聡、小林洋介、中野美和、石崎宏、盧尚建、加藤和雄
    • Organizer
      日本畜産学会第118回大会
    • Place of Presentation
      つくば国際会議場
    • Related Report
      2013 Research-status Report
  • [Presentation] Hormonal regulation of α-tocopherol transfer related molecules expression in bovine mammary epithelial cells2013

    • Author(s)
      芳賀聡、小林洋介、中野美和、石崎宏、盧尚建、加藤和雄
    • Organizer
      2013 アメリカ酪農科学会(ADSA)-アメリカ畜産学会(ASAS)合同年次大会
    • Place of Presentation
      アメリカ インディアナポリス コンベンションセンター
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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