| Project/Area Number |
25871160
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Medical sociology
Gastroenterology
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| Research Institution | National Cancer Center Japan |
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Principal Investigator |
SEKIGUCHI MASAU 独立行政法人国立がん研究センター, 中央病院, がん専門修練医 (50648342)
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| Research Collaborator |
MATSUDA Takahisa
IGARASHI Ataru
SAITO Yutaka
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2013: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 大腸がん検診 / 費用対効果分析 / 大腸内視鏡検査 / 便潜血検査 / 大腸癌検診 / 大腸内視鏡 / 便潜血 / 大腸癌スクリーニング / 全大腸内視鏡検査 / 医療経済 / マルコフモデル |
|---|
| Outline of Final Research Achievements |
There have been few cost-effectiveness analyses of population-based colorectal cancer (CRC) screening in Japan. This study examined the cost-effectiveness of CRC screening with total colonoscopy (TCS) and the fecal immunochemical test (FIT) using Japanese data. We developed a Markov model to assess the cost-effectiveness of three CRC screening strategies: 1) a TCS-based strategy; 2) a FIT-based strategy; 3) a strategy of adding population-wide TCS at a specified age to a FIT-based strategy. Among the three, strategy 1 was the most cost-effective, followed by strategy 3. However, strategy 1 required more than double the number of TCS procedures than the other strategies. Based on the results, we postulate that more active use of TCS than a FIT-based strategy could result in better cost-effectiveness. Considering the cost-effectiveness and TCS workload together, strategy 3 may be an optimal solution.
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