Development of the Rehabilitation method for working memory impairment in patients with schizophrenia
| Project/Area Number |
25871170
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Psychiatric science
Rehabilitation science/Welfare engineering
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| Research Institution | National Center of Neurology and Psychiatry |
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Principal Investigator |
Takeda Kazuyoshi 国立研究開発法人国立精神・神経医療研究センター, 病院, 医員 (00631342)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Keywords | 統合失調症 / 認知リハビリテーション / ワーキングメモリ / 認知機能障害 / 機能的fMRI |
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| Outline of Final Research Achievements |
In patients with schizophrenia, it has been widely accepted that cognitive impairments such as processing speed, attention/vigilance, working memory, verbal learning, visual learning, executive function and social cognition are closely related to the impairment of social functioning. However, the assessment and the treatment of these cognitive impairments have not been fully established. In the present study, we focused on the impairment of working memory, and tried to develop the rehabilitation method based on the neural basis of working memory. By using our developed rehabilitation method, we found that the BACS composite score in post-rehabilitation was significantly higher than that in pre-rehabilitation, suggesting that the our developed rehabilitation method focused on working memory is effectively to improve cognitive functions in patients with schizophrenia.
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Report
(4 results)
Research Products
(1 results)
