Role elucidation of quinones contained in sclerotia grains of Cenococcum geophilum
| Project/Area Number |
25871185
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Applied microbiology
Bio-related chemistry
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| Research Institution | National Institute of Advanced Industrial Science and Technology |
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Principal Investigator |
ITOH Nobuyasu 国立研究開発法人産業技術総合研究所, 物質計測標準研究部門, 主任研究員 (70415644)
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| Co-Investigator(Renkei-kenkyūsha) |
WATANABE Makiko 首都大学東京, 都市環境科学研究科, 教授 (10175119)
SAKAGAMI Nobuo 茨城大学, 農学部, 助教 (00564709)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | ペリレンキノン / 菌核粒子 / Cenococcum geophilum / 役割 / ヒドロキシキノン / ペリレン / 錯形成 / 電子伝達 / ジヒドロキシペリレンキノン / 最小発育阻止濃度（MIC） / pKa |
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| Outline of Final Research Achievements |
Cenococcum geophilum (Cg) is a type of rhizobia and sclerotium grains are resting bodies of Cg found over the world. Sclerotium grains contain a remarkable amount of 4,9-dihydroxyperylene-3,10-quinone (DHPQ), however, its role is still unclear. In this study, I examined the role of DHPQ in sclerotium grains such as "material to keep its structure", "material for electron transfer" and "material for antibiotic property". From the results, DHPQ should play important role for media of electron transfer, defense from radical stresses from outside, or both.
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Report
(4 results)
Research Products
(4 results)
