| Project/Area Number |
25871226
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Radiation science
Urology
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| Research Institution | Aichi Cancer Center Research Institute |
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Principal Investigator |
TOMITA Natsuo 愛知県がんセンター(研究所), 疫学・予防部, 研究員 (60643781)
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| Research Collaborator |
OZE Isao 愛知県がんセンター(研究所), 疫学・予防部, 研究員 (00584509)
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2014: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Keywords | 前立腺癌 / 強度変調放射線治療 / 直腸障害 / 線量制約 / 画像誘導下放射線治療 / 画像誘導放射線治療 |
|---|
| Outline of Final Research Achievements |
The availability of image-guided intensity-modulated radiation therapy is expected for prostate cancer. The late rectal toxicity is the most important problem in high-dose external beam radiation therapy for prostate cancer. Late rectal toxicity was 7.4% after image-guided intensity-modulated radiation therapy in this study. The result of this study indicates that the risk of late rectal toxicity correlates with the rectal volume exposed to high doses of image-guided intensity-modulated radiation therapy, and the percentage of the rectum covered by 70 Gy and 60 Gy are needed to keep below at least 10% and 18%, respectively.
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