Risk factors for type 2 diabetes among individuals with impaired insulin secretion
| Project/Area Number |
25882019
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Applied health science
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| Research Institution | Shiga University of Medical Science |
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Principal Investigator |
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| Project Period (FY) |
2013-08-30 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
|
| Budget Amount *help |
¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | インスリン分泌不全 / インスリン抵抗性 / 糖尿病 / 危険因子 / 2型糖尿病 / コホート研究 |
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| Outline of Final Research Achievements |
This study included individuals without diabetes at baseline who underwent comprehensive medical check-ups at Saku Central Hospital. Moderate and large increases in homeostasis model assessment of insulin resistance (HOMA-IR) had a strong impact on the development of type 2 diabetes regardless of baseline HOMA-IR values among individuals with impaired insulin secretion in this Japanese population. Moreover, metabolic factors had a strong impact on the development of type 2 diabetes among individuals with impaired insulin secretion, compared with individuals with insulin resistance.
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Report
(3 results)
Research Products
(4 results)
