Spatiotemporal analysis of cell movement based on near-infrared responsive stiffness controlled polymeric hydrogels
| Project/Area Number |
25882048
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Biomedical engineering/Biomaterial science and engineering
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| Research Institution | Tokyo University of Science (2014)
National Institute for Materials Science (2013) |
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Principal Investigator |
KAMIMURA Masao 東京理科大学, 基礎工学部, 助教 (80706888)
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| Project Period (FY) |
2013-08-30 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | バイオマテリアル / ゲル / 細胞接着 / ECM / 細胞移動 / メカノバイオロジー / マテリアルバイオロジー / 細胞 / パターニング / ポリエチレングリコール / 細胞外マトリクス |
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| Outline of Final Research Achievements |
The purpose of this study is preparation of near-infrared light stimuli responsive polymeric hydrogel and application for cell culture substrate. Stiffness controlled polyacrylamide gel was prepared as the substrate. Additionally, as a cross-linker, near-infrared excited nanoparticle, rare-earth doped ceramic nanoparticles was also synthesized. The surface of nanoparticle was effectively modified by poly(ethylene glycol) based block copolymer. The obtained materials can be applied for preparation of near-infrared light stimuli responsive polymeric hydrogel.
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Report
(3 results)
Research Products
(12 results)
