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Analysis of nonlinear reaction-diffusion systems for spatial spread of age-structured biological populations

Research Project

Project/Area Number 25887011
Research Category

Grant-in-Aid for Research Activity Start-up

Allocation TypeSingle-year Grants
Research Field Mathematical analysis
Research InstitutionKobe University (2014)
The University of Tokyo (2013)

Principal Investigator

KUNIYA Toshikazu  神戸大学, システム情報学研究科, 講師 (60713013)

Project Period (FY) 2013-08-30 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Keywords感染症 / モデル化 / 関数方程式論 / 解析・評価 / 基本再生産数 / リャプノフ関数 / 年齢構造 / 拡散 / 感染症モデル / 空間構造 / 微分方程式 / 積分方程式 / 力学系 / リャプノフ安定性
Outline of Final Research Achievements

We constructed various nonlinear systems of differential equations as mathematical models for various biological phenomena including the spread of epidemics in society and performed their qualitative analysis. In particular, we focused on the structured population models including the nonlinear systems of reaction-diffusion equations which can take into account both effects of the age-structure and spatial spread of populations. For these models, we derived the basic reproduction number Ro and the corresponding threshold conditions and clarified the relation between them and the mathematical properties such as the existence and stability of each equilibrium. Through these analysis, we applied and extended the theory of related Lyapunov functions to various models.

Report

(3 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Annual Research Report
  • Research Products

    (30 results)

All 2015 2014 2013 Other

All Journal Article (12 results) (of which Peer Reviewed: 11 results,  Acknowledgement Compliant: 8 results) Presentation (16 results) Book (1 results) Remarks (1 results)

  • [Journal Article] Mathematical analysis for an age-structured HIV infection model with saturation infection rate2015

    • Author(s)
      J. Wang, R. Zhang, T. Kuniya
    • Journal Title

      Electron. J. Diff. Equ.

      Volume: 33 Pages: 1-19

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] The stability analysis of an SVEIR model with continuous age-structure in the exposed and infectious classes2015

    • Author(s)
      J. Wang, R. Zhang, T. Kuniya
    • Journal Title

      J. Biol. Dyn.

      Volume: 9 Issue: 1 Pages: 73-101

    • DOI

      10.1080/17513758.2015.1006696

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] A delayed multi-group SIS epidemic model with nonlinear incidence rates and patch structure2015

    • Author(s)
      [5] Y. Muroya, T. Kuniya and J. Wang
    • Journal Title

      J. Math. Anal. Appl.

      Volume: 425 Issue: 1 Pages: 415-439

    • DOI

      10.1016/j.jmaa.2014.12.019

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Existence result for an age-structured SIS epidemic model with spatial diffusion2015

    • Author(s)
      T. Kuniya, R. Oizumi
    • Journal Title

      Nonlinear Anal. RWA

      Volume: 23 Pages: 196-208

    • DOI

      10.1016/j.nonrwa.2014.10.006

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Global stability of nonresident computer virus models2015

    • Author(s)
      Y. Muroya, T. Kuniya
    • Journal Title

      Math. Meth. Appl. Sci.

      Volume: 38 Issue: 2 Pages: 281-295

    • DOI

      10.1002/mma.3068

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Stability of epidemic models with waning immunity2014

    • Author(s)
      Y. Nakata, Y. Enatsu, H. Inaba, T. Kuniya, Y. Muroya, Y. Takeuchi
    • Journal Title

      SUT J. Math.

      Volume: 50 Pages: 205-246

    • NAID

      120006397889

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Further stability analysis of a multi-group SIRS epidemic model with varying total population sizes2014

    • Author(s)
      [7] Y. Muroya and T. Kuniya
    • Journal Title

      Appl. Math. Letters

      Volume: 38 Pages: 73-78

    • DOI

      10.1016/j.aml.2014.07.005

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Threshold dynamics of an SIR epidemic model with a hybrid of multi-group and patch structures2014

    • Author(s)
      [6] T. Kuniya, Y. Muroya and Y. Enatsu
    • Journal Title

      Math. Bios. Eng.

      Volume: 11 Issue: 6 Pages: 1375-1393

    • DOI

      10.3934/mbe.2014.11.1375

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Global stability of a multi-group SIS epidemic model for population migration2014

    • Author(s)
      T. Kuniya, Y. Muroya
    • Journal Title

      Discrete and Continuous Dynamical Systems - Series B

      Volume: 19 Pages: 1105-1118

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A note on global stability for malaria infections model with latencies2014

    • Author(s)
      J. Wang, J. Pang, T. Kuniya
    • Journal Title

      Mathematical Biosciences and Engineering

      Volume: 11 Issue: 4 Pages: 995-1001

    • DOI

      10.3934/mbe.2014.11.995

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Existence of a nontrivial periodic solution in an age-structured SIR epidemic model with time periodic coefficients2014

    • Author(s)
      T. Kuniya
    • Journal Title

      Applied Mathematics Letters

      Volume: 27 Pages: 15-20

    • DOI

      10.1016/j.aml.2013.08.008

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] グラフ理論的なリアプノフ汎関数の手法に対するmax 関数のアイデア2013

    • Author(s)
      國谷紀良
    • Journal Title

      数理解析研究所講究録

      Volume: 1853 Pages: 84-90

    • Related Report
      2013 Annual Research Report
  • [Presentation] 空間異質性を持つ年齢構造化SIS感染症モデルの漸近挙動2015

    • Author(s)
      國谷紀良
    • Organizer
      日本数学会2015年度年会
    • Place of Presentation
      明治大学駿河台キャンパス(東京都千代田区神田)
    • Year and Date
      2015-03-22
    • Related Report
      2014 Annual Research Report
  • [Presentation] 多次元ODEとしての感染症の数理モデルに対する漸近安定性解析2014

    • Author(s)
      國谷紀良
    • Organizer
      実領域における常微分方程式の定性的理論とその応用
    • Place of Presentation
      京都大学数理解析研究所(京都府京都市)
    • Year and Date
      2014-11-05
    • Related Report
      2014 Annual Research Report
  • [Presentation] 空間構造を含む年齢構造化感染症モデルにおけるエンデミックな平衡解の存在について2014

    • Author(s)
      國谷紀良
    • Organizer
      感染症数理モデルの実用化と産業及び政策での活用のための新たな展開
    • Place of Presentation
      JR博多シティ会議場(福岡県福岡市)
    • Year and Date
      2014-10-02
    • Related Report
      2014 Annual Research Report
  • [Presentation] 空間拡散を考慮に入れた年齢構造化SIS感染症モデルの解析2014

    • Author(s)
      國谷紀良
    • Organizer
      日本数学会2014年度秋季総合分科会
    • Place of Presentation
      広島大学東広島キャンパス(広島県東広島市)
    • Year and Date
      2014-09-27
    • Related Report
      2014 Annual Research Report
  • [Presentation] 空間構造と年齢構造を含む感染症モデルにおける非自明平衡解の存在2014

    • Author(s)
      國谷紀良
    • Organizer
      第11回生物数学の理論とその応用
    • Place of Presentation
      京都大学数理解析研究所(京都府京都市)
    • Year and Date
      2014-09-16
    • Related Report
      2014 Annual Research Report
  • [Presentation] 空間拡散を含む年齢構造化 SIS 感染症モデルにおける平衡解の存在2014

    • Author(s)
      國谷紀良
    • Organizer
      日本応用数理学会2014年度年会
    • Place of Presentation
      政策研究大学院大学(東京都港区六本木)
    • Year and Date
      2014-09-05
    • Related Report
      2014 Annual Research Report
  • [Presentation] 拡散項を含む年齢構造化 SIS 感染症モデルの解析2014

    • Author(s)
      國谷紀良
    • Organizer
      第36回発展方程式若手セミナー
    • Place of Presentation
      休暇村南阿蘇(熊本県阿蘇郡高森町)
    • Year and Date
      2014-08-29
    • Related Report
      2014 Annual Research Report
  • [Presentation] On the invariance principle appearing in Lyapunov functional techniques for structured population models2014

    • Author(s)
      T. Kuniya
    • Organizer
      JSMB/SMB 2014 Osaka
    • Place of Presentation
      Osaka International Convention Center
    • Year and Date
      2014-07-30
    • Related Report
      2014 Annual Research Report
  • [Presentation] Existence of endemic periodic solutions in age-structured epidemic models2014

    • Author(s)
      T. Kuniya
    • Organizer
      JSMB/SMB 2014 Osaka
    • Place of Presentation
      Osaka International Convention Center
    • Year and Date
      2014-07-29
    • Related Report
      2014 Annual Research Report
  • [Presentation] 年齢変数を含む非線形偏微分方程式の漸近解析における不変性原理とリャプノフ汎函数の手法について

    • Author(s)
      國谷紀良
    • Organizer
      日本数学会2014年度年会
    • Place of Presentation
      学習院大学目白キャンパス
    • Related Report
      2013 Annual Research Report
  • [Presentation] 年齢構造化多状態SIR感染症モデルに対する不変性原理とリャプノフ汎函数について

    • Author(s)
      國谷紀良
    • Organizer
      構造化感染症モデルの動態
    • Place of Presentation
      岡山大学津島キャンパス
    • Related Report
      2013 Annual Research Report
  • [Presentation] Invariance principle and Lyapunov functionals for age-structured population models

    • Author(s)
      T. Kuniya
    • Organizer
      International Workshop on Biomathematics Modelling and Its Dynamical Analysis
    • Place of Presentation
      Harbin
    • Related Report
      2013 Annual Research Report
  • [Presentation] 多状態年齢構造化SIR感染症モデルの大域的安定性

    • Author(s)
      國谷紀良
    • Organizer
      第10回生物数学の理論とその応用
    • Place of Presentation
      京都大学数理解析研究所
    • Related Report
      2013 Annual Research Report
  • [Presentation] 年齢構造を含む多状態SIR感染症モデルの安定性解析

    • Author(s)
      國谷紀良
    • Organizer
      感染症流行モデリング:理論、実践とシミュレーションのギャップを埋める
    • Place of Presentation
      東京大学本郷キャンパス
    • Related Report
      2013 Annual Research Report
  • [Presentation] 季節依存性を持つ感染症の流行動態モデルにおける基本再生産数R0の閾値的性質の解析

    • Author(s)
      國谷紀良, 稲葉寿
    • Organizer
      第23回日本数理生物学会年会
    • Place of Presentation
      静岡大学浜松キャンパス
    • Related Report
      2013 Annual Research Report
  • [Presentation] 感染症の季節的流行モデルとしての非線形偏微分方程式の解析

    • Author(s)
      國谷紀良
    • Organizer
      日本応用数理学会2013年度年会
    • Place of Presentation
      アクロス福岡
    • Related Report
      2013 Annual Research Report
  • [Book] 人口と感染症の数理:年齢構造ダイナミクス入門2014

    • Author(s)
      ミンモ・イアネリ, 稲葉寿, 國谷紀良
    • Total Pages
      206
    • Publisher
      東京大学出版会
    • Related Report
      2014 Annual Research Report
  • [Remarks] Toshikazu Kuniya

    • URL

      https://sites.google.com/site/toshikazukuniya/home

    • Related Report
      2014 Annual Research Report

URL: 

Published: 2013-09-12   Modified: 2019-07-29  

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