| Project/Area Number |
25889065
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Biofunction/Bioprocess
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| Research Institution | Nara National College of Technology |
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Principal Investigator |
HAYASHI Keita 奈良工業高等専門学校, その他部局等, 助教 (10710783)
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| Project Period (FY) |
2013-08-30 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | Drug Delivery System / Self-assembly / Vesicle / vesicle / self-assembly / drug delivery system |
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| Outline of Final Research Achievements |
It has been investigated to active targeting for cancer cells by using biomolecules, such as anti-body and lectin. Drug encapsulating vesicles, such as liposomes and niosomes, were immobilized by these biomolecules in order to deliver efficiently and specifically drug for cancer cells. In recent years, Development of cancer cell targeting biomolecules has been investigated frequently. On the other hand, it has been hardly investigated about an optimal vesicle in spite of development of various kinds of vesicles. In this study, not only cancer cell targeting biomolecules, but also an optimal vesicle has been investigated. This result supported to improve drug delivery efficiency.
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