Development of the tailor-made biosynthesis system of aromatic compounds using microbe
| Project/Area Number |
25889071
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Biofunction/Bioprocess
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| Research Institution | The Institute of Physical and Chemical Research |
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Principal Investigator |
NODA Shuhei 独立行政法人理化学研究所, 環境資源科学研究センター, 特別研究員 (30710131)
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| Project Period (FY) |
2013-08-30 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | Kluyveromyces lactis / NADPH / アセチル-CoA / Tyrosine decarboxylase / Saccharomyces cerevisiae |
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| Outline of Final Research Achievements |
And it was cultured characterization for a variety of yeast , were screened for ethanol non-production type yeast . As a result , we have found that for the kind of Kluyveromyces lactis, hardly produce ethanol . As a result of this K. further lactis strain analysis , coenzymes and the like ATP and NADPH involved in the conversion into various useful substances , are important intracellular substance such as acetyl coenzyme A to be the skeleton of various useful substances , S . it was found that are significantly more storage compared to cerevisiae. K. lactis were screened in this study , suggesting that it can become a platform for the production by fermentation of various useful substances. In addition, some enzymes to modify aromatic residues can be successfully screened. We here constructed research base for "tailor-made biosynthesis system of aromatic compounds."
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Report
(3 results)
Research Products
(5 results)
