Mechanism of miRNA-mediated translational repression in plants
Project/Area Number |
25891006
|
Research Category |
Grant-in-Aid for Research Activity Start-up
|
Allocation Type | Single-year Grants |
Research Field |
Molecular biology
|
Research Institution | The University of Tokyo |
Principal Investigator |
|
Project Period (FY) |
2013-08-30 – 2015-03-31
|
Project Status |
Completed (Fiscal Year 2014)
|
Budget Amount *help |
¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
|
Keywords | RNAサイレンシング / 核酸 / 蛋白質 / 発現制御 |
Outline of Final Research Achievements |
Plant microRNAs (miRNAs) can mediate the cleavage of their target mRNAs as well as the repression of their translation. However, the molecular mechanism underlying miRNA-mediated translational repression remains unknown. Here, by using an in vitro system prepared from plant culture cells, we biochemically dissected the mechanisms of miRNA-mediated gene silencing.
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Report
(3 results)
Research Products
(6 results)