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Inhaled hydrogen gas therapy for the prevention of lung transplant-induced ischemia-reperfusion injury

Research Project

Project/Area Number 25893118
Research Category

Grant-in-Aid for Research Activity Start-up

Allocation TypeSingle-year Grants
Research Field Respiratory surgery
Research InstitutionOsaka University

Principal Investigator

TOMOHIRO Kawamura  大阪大学, 医学(系)研究科(研究院), 助教 (30528675)

Project Period (FY) 2013-08-30 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords移植・再生医療 / 水素 / 肺移植 / 外科 / 酸化ストレス
Outline of Final Research Achievements

Our basic data have shown that hydrogen is a high potential therapeutic gas for the lung transplant-induced ischemia-reperfusion injury. To introduce the hydrogen gas therapy to clinical practice, we developed the ventilation system with hydrogen. And we have started to administer hydrogen gas to the patient. On the other hand, to elucidate the mechanism of the therapeutic effect of hydrogen gas, we also set up the cell experiment system with hydrogen.

Report

(3 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Annual Research Report
  • Research Products

    (4 results)

All 2015 2014 Other

All Presentation (2 results) Book (1 results) Remarks (1 results)

  • [Presentation] 水素に依る肺移植後虚血再灌流傷害の軽減2015

    • Author(s)
      川村知裕
    • Organizer
      第115回日本外科学会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2015-04-16
    • Related Report
      2014 Annual Research Report
  • [Presentation] 肺移植ドナーに対する水素ガス吸入による肺移植後虚血再灌流傷害軽減2014

    • Author(s)
      川村知裕
    • Organizer
      第41回日本臓器保存生物医学会学術集会
    • Place of Presentation
      千里ライフサイエンスセンター
    • Year and Date
      2014-11-28
    • Related Report
      2014 Annual Research Report
  • [Book] 今日の移植 2015年1月号2015

    • Author(s)
      川村知裕
    • Total Pages
      2
    • Publisher
      日本医学館
    • Related Report
      2014 Annual Research Report
  • [Remarks] 大阪大学呼吸器外科 「呼吸器外科の研究」「肺移植」

    • URL

      http://www.thoracic.med.osaka-u.ac.jp/jp/medical/index.html

    • Related Report
      2013 Annual Research Report

URL: 

Published: 2013-09-12   Modified: 2019-07-29  

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