Inhaled hydrogen gas therapy for the prevention of lung transplant-induced ischemia-reperfusion injury

Research Project

Project/Area Number	25893118
Research Category	Grant-in-Aid for Research Activity Start-up
Allocation Type	Single-year Grants
Research Field	Respiratory surgery
Research Institution	Osaka University
Principal Investigator	TOMOHIRO Kawamura 大阪大学, 医学(系)研究科(研究院), 助教 (30528675)
Project Period (FY)	2013-08-30 – 2015-03-31
Project Status	Completed (Fiscal Year 2014)
Budget Amount *help	¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000) Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000) Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords	移植・再生医療 / 水素 / 肺移植 / 外科 / 酸化ストレス
Outline of Final Research Achievements	Our basic data have shown that hydrogen is a high potential therapeutic gas for the lung transplant-induced ischemia-reperfusion injury. To introduce the hydrogen gas therapy to clinical practice, we developed the ventilation system with hydrogen. And we have started to administer hydrogen gas to the patient. On the other hand, to elucidate the mechanism of the therapeutic effect of hydrogen gas, we also set up the cell experiment system with hydrogen.

Report

(3 results)