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Basic research for the collaterogenesis in coronary circulation

Research Project

Project/Area Number 25893187
Research Category

Grant-in-Aid for Research Activity Start-up

Allocation TypeSingle-year Grants
Research Field Cardiovascular medicine
Research InstitutionKumamoto University

Principal Investigator

ARIMA Yuichiro  熊本大学, 医学部附属病院, 助教 (60706414)

Project Period (FY) 2013-08-30 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords側副血行路 / 冠動脈 / 冠循環 / 比較解剖 / 発生
Outline of Final Research Achievements

We developed two techniques to visualize the coronary architecture. The micro X-ray CT enabled to understand whole architecture of the coronary vasculature. Bi-phasic endothelial labeling distinguished open and close coronary microcirculation in coronary ligated mice.
Furthermore, to understand the coronary homology between species, we analyze the anatomical characteristics in urodele amphibia. Compare to mammals, urodele coronary circulation are quite few on the surface of ventricle. However, conal region was covered by rich vascular network. And the drainage vessel connected to the sinus venosus. These findings were reported on the 78th and 79th Japanese cardiovascular society annual meeting.

Report

(3 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Annual Research Report
  • Research Products

    (6 results)

All 2015 2014

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (4 results) (of which Invited: 1 results)

  • [Journal Article] Prolonged hyponatremia due to hypopituitarism in a patient with non-ST-elevation myocardial infarction2014

    • Author(s)
      Kyohei Marume, Yuichiro Arima, Motoyuki Igata, Takeshi Nishikawa, Eiichiro Yamamoto, Megumi Yamamuro, Kenichi Tsujita, Tomoko Tanaka, Koichi Kaikita, Seiji Hokimoto, Hisao Ogawa
    • Journal Title

      Journal of Cardiology Cases

      Volume: 10 Pages: 226-230

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Comparison of the effect of CYP2C19 polymorphism on clinical outcome between acute coronary syndrome and stable angina2014

    • Author(s)
      Yuichiro Arima, Seiji Hokimoto, Tomonori Akasaka, Koichi Mizobe, Koichi Kaikita, Kentaro Oniki, Kazuko Nakagawa, Hisao Ogawa
    • Journal Title

      Journal of cardiology

      Volume: 14 Issue: 6 Pages: 221-224

    • DOI

      10.1016/j.jjcc.2014.07.016

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Presentation] Slow Growth in Fetal Life as the Risk of Non-Congenital Heart Diseases in Adult2015

    • Author(s)
      Yuichiro Arima
    • Organizer
      第79回日本循環器学会学術集会
    • Place of Presentation
      大阪リーガロイヤルホテル
    • Year and Date
      2015-04-24 – 2015-04-26
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] In vivo imaging of the coronary circulation of the amphibia2014

    • Author(s)
      Yuichiro Arima
    • Organizer
      第78回日本循環器学会学術集会
    • Place of Presentation
      東京国際フォーラム
    • Related Report
      2013 Annual Research Report
  • [Presentation] In Vivo Imaging of the Coronary Circulation of the Amphibia2014

    • Author(s)
      Yuichiro Arima
    • Organizer
      The 18th international vascular biology meeting
    • Place of Presentation
      京都みやこめっせ
    • Related Report
      2013 Annual Research Report
  • [Presentation] Comparative Anatomy of the Coronary Circulation among Rodent Species2014

    • Author(s)
      Yuichiro Arima
    • Organizer
      The 18th international vascular biology meeting
    • Place of Presentation
      京都みやこめっせ
    • Related Report
      2013 Annual Research Report

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Published: 2013-09-12   Modified: 2019-07-29  

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