| Project/Area Number |
25893188
|
|---|
| Research Category |
Grant-in-Aid for Research Activity Start-up
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Neurosurgery
|
|---|
| Research Institution | Kumamoto University |
|---|
Principal Investigator |
|
|---|
| Research Collaborator |
ANAI Shigeo 熊本大学, 医学部附属病院, 特任助教
|
|---|
| Project Period (FY) |
2013-08-30 – 2015-03-31
|
| Project Status |
Completed (Fiscal Year 2014)
|
| Budget Amount *help |
¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
|
|---|
| Keywords | 悪性グリオーマ / ドラッグデリバリーシステム / フィブリン糊 / 局所治療 / 初代培養株 / テモゾロミド / トランスレーショナルリサーチ / 癌 / 神経科学 |
|---|
| Outline of Final Research Achievements |
The purpose of this project is to develop a novel strategy for preventing local recurrence of malignant glioma, because it is usually difficult due to blood-brain barrier.
I investigated that local administration of high concentration of temozolomide with fibrin glue could prevent tumor growth of primary malignant glioma xenografts derived from human glioblastoma.
|
