| Project/Area Number |
25893191
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Human pathology
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| Research Institution | Kagoshima University |
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Principal Investigator |
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| Project Period (FY) |
2013-08-30 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 早期胃癌 / 粘膜筋板 / ムチン抗原 / 内視鏡的切除 / 病理学 / 粘膜内癌 / ＥＳＤ |
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| Outline of Final Research Achievements |
In early gastric cancers, there is no discrimination between (1) the case with intramucosal proliferation showing no muscularis mucosae invasion (abbreviated as “pT1a1-M” ) and (2) the case with intramucosal proliferation showing muscularis mucosae invasion (abbreviated as “pT1a2-MM” ). Both of them are classified into the same depth invasion criteria, abbreviated as pT1a (M), not only in UICC but also in the Japanese Classification of Gastric Carcinoma. In the present study, “pT1a2-MM” showed higher rates of vessel permeation, lymph node metastasis, and the positive MUC1/DF3 expression than “pT1a1-M”. Therefore “pT1a1-M” and “pT1a2-MM” should be divided.
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