• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Molecular biological study of cells sheet derived from human dental follicle for bone regenerative medicine

Research Project

Project/Area Number 25893263
Research Category

Grant-in-Aid for Research Activity Start-up

Allocation TypeSingle-year Grants
Research Field Surgical dentistry
Research InstitutionNihon University

Principal Investigator

TAKAHASHI Kosuke  日本大学, 松戸歯学部, 助教 (30705687)

Project Period (FY) 2013-08-30 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords歯嚢細胞 / 細胞シート / 骨再生 / 未分化間葉系幹細胞 / 石灰化能 / 歯嚢由来間葉系幹細胞 / 免疫組織化学染色 / 骨芽細胞分化
Outline of Final Research Achievements

The dental follicle is an ectomesenchymally derived from the neural crest, which has connective tissue surrounding the tooth germ that contains stem cells and/or progenitor cells of the periodontium. Human dental follicle cells (hDFCs) have the ability to mineralize under in vitro culture using osteogenic induction medium. Cell sheet engineering is an emerging technology that is being researched for several tissue.This technique involves culturing cells to hyperconfluence and inducing matrix production for the formation of a robust tissue sheet. In this study, we investigate the abillity of cell che10516et derived from dental follicle cells for bone regeneration

Report

(3 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Annual Research Report
  • Research Products

    (5 results)

All 2015 2014 2013

All Journal Article (2 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results,  Acknowledgement Compliant: 1 results) Presentation (3 results)

  • [Journal Article] MicroRNA-29 Family Suppresses Mineralization in Dental Follicle Cells2015

    • Author(s)
      Risa tomoki,naomi ogura,kosuke takahashi
    • Journal Title

      Journal of Hard Tissue Biology

      Volume: 24 Pages: 23-28

    • NAID

      130004848438

    • Related Report
      2014 Annual Research Report
  • [Journal Article] Applicability of human dental follicle cells to bone regeneration without dexamethasone: an in vivo pilot study.2014

    • Author(s)
      takahasi kosuke
    • Journal Title

      International journal of macillofacial surgery

      Volume: 14 Issue: 5 Pages: 436-436

    • DOI

      10.1016/j.ijom.2014.11.006

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] Gene Expression of Semaphorin 7A in Human Dental Follicle Cells2014

    • Author(s)
      kosuke takahashi
    • Organizer
      American assosiation of oral and maxillofacial surgery
    • Place of Presentation
      Hawai USA
    • Year and Date
      2014-09-09 – 2014-09-14
    • Related Report
      2014 Annual Research Report
  • [Presentation] 歯嚢細胞の骨芽細胞分化におけるPRGFの影響2014

    • Author(s)
      岡田仁恵・高橋康輔
    • Organizer
      第68回日本口腔科学会
    • Place of Presentation
      東京都新宿区京王プラザホテル
    • Related Report
      2013 Annual Research Report
  • [Presentation] ヒト歯嚢由来細胞の骨芽細胞分化過程における網羅的MicroRNAの発現解析2013

    • Author(s)
      友木里沙・高橋康輔
    • Organizer
      第58回日本口腔外科学会
    • Place of Presentation
      福岡県博多市福岡国際会議場
    • Related Report
      2013 Annual Research Report

URL: 

Published: 2013-09-12   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi