Single cell analysis of the origin and evolution of chordates: notochord, neural tubes and somites

Research Project

Project/Area Number	25K09656
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Multi-year Fund
Section	一般
Review Section	Basic Section 44020:Developmental biology-related
Research Institution	National Institute for Basic Biology
Principal Investigator	高橋弘樹基礎生物学研究所, 分野横断研究ユニット, 助教 (40283585)
Project Period (FY)	2025-04-01 – 2030-03-31
Project Status	Granted (Fiscal Year 2025)
Budget Amount *help	¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000) Fiscal Year 2029: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000) Fiscal Year 2028: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000) Fiscal Year 2027: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000) Fiscal Year 2026: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000) Fiscal Year 2025: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Keywords	脊索動物 / 脊索 / 神経管 / 体節
Outline of Research at the Start	脊索動物(頭索動物+尾索動物+脊椎動物)の脊索・神経管・体節は脊索動物体制の確立に至る重要な形質である。脊索動物で最も祖先的な頭索動物ナメクジウオを中心に脊索動物に特徴的な脊索・神経管・体節のシングルセル解析(単一細胞遺伝子解析)により脊索動物の起源と進化を解き明かす。