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exploration of senescent immune cells after umbilical cord blood transplantation

Research Project

Project/Area Number 25K10693
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 52010:General internal medicine-related
Research InstitutionShowa Medical University

Principal Investigator

服部 憲路  昭和医科大学, 医学部, 教授 (30453624)

Co-Investigator(Kenkyū-buntansha) 荒井 奈々  昭和医科大学, 医学部, 助教 (50761219)
綿貫 めぐみ  昭和医科大学, 医学部, 助教 (50990884)
Project Period (FY) 2025-04-01 – 2028-03-31
Project Status Granted (Fiscal Year 2025)
Budget Amount *help
¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2027: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2026: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2025: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords造血幹細胞移植
Outline of Research at the Start

造血細胞移植におけるドナー造血幹細胞および免疫細胞は、造血細胞移植をうけるレシピエントにとって予後を左右する重要な因子である。本研究は、移植前と移植後のドナー造血幹細胞および免疫細胞をシングルセルRNA-Seqを用いて解析し、その動態を解明する。

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Published: 2025-04-17   Modified: 2025-06-20  

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