肺非結核性抗酸菌症の感染経路と細菌叢解析や宿主細胞機能解析による包括的な病態把握

Research Project

Project/Area Number	25K10722
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Multi-year Fund
Section	一般
Review Section	Basic Section 52010:General internal medicine-related
Research Institution	University of Occupational and Environmental Health, Japan
Principal Investigator	山崎啓産業医科大学, 医学部, 准教授 (50441861)
Project Period (FY)	2025-04-01 – 2028-03-31
Project Status	Granted (Fiscal Year 2025)
Budget Amount *help	¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000) Fiscal Year 2027: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000) Fiscal Year 2026: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000) Fiscal Year 2025: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords	非結核性抗酸菌症
Outline of Research at the Start	気管支肺胞洗浄液を用いた肺非結核性抗酸菌症（肺NTM症）患者の病巣内における抗酸菌種とその割合（菌叢）、生活環境中の検体（シャワーヘッドなど）内の非結核性抗酸菌の菌叢を培養によらない分子生物学的手法で詳細に菌種を調査し、NTMの感染経路を明らかにする。