Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2027: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2026: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2025: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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Outline of Research at the Start |
Recent research indicates that the gut-brain axis (communication between CNS, intestines and microbiota) plays an important role in autoimmune diseases such as multiple sclerosis (MS). However, much remains unknown in this complex field. We have previously reported a therapeutic potential of targeting a subset of NKT cells, unconventional T cells that share properties of both T cells and NK cells. In this research, I aim to identify novel pathogenic immune cell populations potentially associated with the gut-brain axis in MS, using mouse models with a particular focus on NKT cells.
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