Investigation of the effects of dietary lipids on intestinal barrier function and the food components that contribute to its improvement

Research Project

Project/Area Number	25K16890
Research Category	Grant-in-Aid for Early-Career Scientists
Allocation Type	Multi-year Fund
Review Section	Basic Section 08030:Family and consumer sciences, and culture and living-related
Research Institution	Nara Women's University
Principal Investigator	菅尚子奈良女子大学, 生活環境科学系, 助教 (50908168)
Project Period (FY)	2025-04-01 – 2028-03-31
Project Status	Granted (Fiscal Year 2025)
Budget Amount *help	¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000) Fiscal Year 2027: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000) Fiscal Year 2026: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000) Fiscal Year 2025: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Keywords	脂質 / 腸管バリア
Outline of Research at the Start	本研究では、異なる脂肪酸および油脂が腸管バリアと免疫機能に与える影響を細胞・動物モデルで検討し、さらに食事パターンの影響も評価する。これにより、油脂選択の重要性に関する新たな知見を提供し、腸管バリア機能障害に関わる疾患への食事療法の発展に貢献することを目指す。