The Role of Plastic Additives in Metabolic Syndrome: Analyzing Adiponectin and Leptin Biomarkers in Japanese Children

Research Project

Project/Area Number	25K20566
Research Category	Grant-in-Aid for Early-Career Scientists
Allocation Type	Multi-year Fund
Review Section	Basic Section 58020:Hygiene and public health-related: including laboratory approach
Research Institution	Hokkaido University
Principal Investigator	KETEMA RAHEL・MESFIN 北海道大学, 環境健康科学研究教育センター, 博士研究員 (60964822)
Project Period (FY)	2025-04-01 – 2028-03-31
Project Status	Granted (Fiscal Year 2025)
Budget Amount *help	¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000) Fiscal Year 2027: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000) Fiscal Year 2026: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000) Fiscal Year 2025: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords	plastic additives / metabolic syndrome / adiponectin / leptin / phthalates
Outline of Research at the Start	This study will examine how exposure to plastic-related chemicals, named phthalates and alternative plasticizers, at prenatal and postnatal stages affects children's metabolic health by measuring chemical levels and related metabolic biomarkers.