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Precise metal array methods using a template ranged from one atom to biomacromolecules

Research Project

Project/Area Number 26248016
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Inorganic chemistry
Research InstitutionThe University of Tokyo

Principal Investigator

Shionoya Mitsuhiko  東京大学, 大学院理学系研究科(理学部), 教授 (60187333)

Co-Investigator(Renkei-kenkyūsha) TASHIRO Shohei  東京大学, 大学院理学系研究科, 准教授 (80420230)
UBE Hitoshi  東京大学, 大学院理学系研究科, 助教 (00512138)
TAKEZAWA Yusuke  東京大学, 大学院理学系研究科, 助教 (70508598)
Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥41,990,000 (Direct Cost: ¥32,300,000、Indirect Cost: ¥9,690,000)
Fiscal Year 2016: ¥16,250,000 (Direct Cost: ¥12,500,000、Indirect Cost: ¥3,750,000)
Fiscal Year 2015: ¥12,220,000 (Direct Cost: ¥9,400,000、Indirect Cost: ¥2,820,000)
Fiscal Year 2014: ¥13,520,000 (Direct Cost: ¥10,400,000、Indirect Cost: ¥3,120,000)
Keywords超分子金属錯体 / 金属配列 / 大環状配位子 / 人工DNA / 鋳型分子 / 超分子錯体 / 鋳型合成 / 金属錯体 / 鋳型配位子
Outline of Final Research Achievements

Precise control of metal arrangement in nano-scale is essential to create new electronic structures based on the number, kind, and arrangement of metal ions. In this research, we have developed three types of new template ligands such as “atomic frames”, “synthetic molecules”, and “biomolecules” to flexibly arrange finite or infinite metal ions in lines or circles. Furthermore, we have also demonstrated that such metal array structures or metal complexes can be applied to several functions including catalytic reactions or the control of molecular motions.

Report

(4 results)
  • 2017 Final Research Report ( PDF )
  • 2016 Annual Research Report
  • 2015 Annual Research Report
  • 2014 Annual Research Report
  • Research Products

    (16 results)

All 2017 2016 2015 Other

All Int'l Joint Research (3 results) Journal Article (6 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 6 results,  Open Access: 4 results,  Acknowledgement Compliant: 1 results) Presentation (5 results) (of which Int'l Joint Research: 5 results,  Invited: 5 results) Remarks (2 results)

  • [Int'l Joint Research] Birmingham University(英国)

    • Related Report
      2016 Annual Research Report
  • [Int'l Joint Research] University of Munster(Germany)

    • Related Report
      2016 Annual Research Report
  • [Int'l Joint Research] University of Birmingham(英国)

    • Related Report
      2015 Annual Research Report
  • [Journal Article] Synthesis of a Truncated Analog of Amphidinol 3 Corresponding to the C21-C39/C52-C67 Section2017

    • Author(s)
      Makoto Ebine, Yuri Takada, Naoto Yanai, and Tohru Oishi
    • Journal Title

      Chemistry Letters

      Volume: 46 Issue: 5 Pages: 662-664

    • DOI

      10.1246/cl.160985

    • NAID

      130005655669

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Enzymatic Synthesis of Ligand-bearing DNAs for Metal-mediated Base Pairing Utilising a Template-independent DNA Polymerase2016

    • Author(s)
      T. Kobayashi, Y. Takezawa, A. Sakamoto, M. Shionoya
    • Journal Title

      Chemical Communications

      Volume: 52 Issue: 19 Pages: 3762-3765

    • DOI

      10.1039/c5cc10039a

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Metal-responsive structural transformation between artificial DNA duplexes and three-way junctions2016

    • Author(s)
      Yusuke Takezawa, Shuhei Yoneda, Jean-Louis H. A. Duprey, Takahiro Nakama and Mitsuhiko Shionoya
    • Journal Title

      Chem. Sci.

      Volume: 7 Issue: 5 Pages: 3006-3010

    • DOI

      10.1039/c6sc00383d

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The Effects of Magnesium Ions on the Enzymatic Synthesis of Ligand-Bearing Artificial DNA by Template-Independent Polymerase2016

    • Author(s)
      Yusuke Takezawa, Teruki Kobayashi and Mitsuhiko Shionoya
    • Journal Title

      Int. J. Mol. Sci.

      Volume: 17 Issue: 6 Pages: 906-906

    • DOI

      10.3390/ijms17060906

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] pH-Dependence of the Thermal Stability of Metallo-DNA Duplexes Containing Ligand-Type 5-Hydroxyuracil Nucleobases2016

    • Author(s)
      Kotaro Nishiyama, Yusuke Takezawa, Mitsuhiko Shionoya
    • Journal Title

      Inorg. Chim. Acta

      Volume: 452 Pages: 176-180

    • DOI

      10.1016/j.ica.2016.04.040

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Bifacial Base-Pairing Behaviors of 5-Hydroxyuracil DNA Bases Both through Hydrogen Bonding and Metal Coordination2015

    • Author(s)
      Takezawa, Y., Nishiyama K., Mashima T., Katahira, M. and Shionoya, M.
    • Journal Title

      Chemistry

      Volume: 21 Issue: 42 Pages: 14713-14716

    • DOI

      10.1002/chem.201502772

    • Related Report
      2015 Annual Research Report 2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] Metal-based Supramolecular Array, Space and Motion2017

    • Author(s)
      Mitsuhiko Shionoya
    • Organizer
      ResMoSys
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] NANOSPACE-SPECIFIC MOLECULAR BEHAVIORS2017

    • Author(s)
      Mitsuhiko Shionoya
    • Organizer
      Asian Conference on Coordination Chemistry
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Supramolecular Design for Metal Array, Space, and Motion2016

    • Author(s)
      Mitsuhiko Shionoya
    • Organizer
      Chile-Japan Academic Forum 2016: Satellite Meeting at Santiago
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Molecular Designing for Serendipity in Supramolecular Chemistry2015

    • Author(s)
      Mitsuhiko Shionoya
    • Organizer
      5th International Conference for Young Chemists
    • Place of Presentation
      Penang (Malaysia)
    • Year and Date
      2015-08-05
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Metal-mediated Base Pairing in DNA: Alternatives to Hydrogen-bonded Watson-Crick Base Pairs2015

    • Author(s)
      Mitsuhiko Shionoya
    • Organizer
      ISABC13
    • Place of Presentation
      Galway (Ireland)
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Remarks] 塩谷研究室

    • URL

      http://www.chem.s.u-tokyo.ac.jp/users/bioinorg/index.html

    • Related Report
      2016 Annual Research Report
  • [Remarks] 塩谷研究室 Bioinorganic Chemistry Laboratory

    • URL

      http://www.chem.s.u-tokyo.ac.jp/users/bioinorg/index.html

    • Related Report
      2015 Annual Research Report

URL: 

Published: 2014-04-04   Modified: 2022-02-22  

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