| Co-Investigator(Kenkyū-buntansha) |
江馬 一弘 上智大学, 理工学部, 教授 (40194021)
南部 伸孝 上智大学, 理工学部, 教授 (00249955)
遠藤 明 上智大学, 理工学部, 准教授 (00119124)
橋本 剛 上智大学, 理工学部, 准教授 (20333049)
|
|---|
| Budget Amount *help |
¥41,990,000 (Direct Cost: ¥32,300,000、Indirect Cost: ¥9,690,000)
Fiscal Year 2018: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2017: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2016: ¥7,540,000 (Direct Cost: ¥5,800,000、Indirect Cost: ¥1,740,000)
Fiscal Year 2015: ¥11,310,000 (Direct Cost: ¥8,700,000、Indirect Cost: ¥2,610,000)
Fiscal Year 2014: ¥13,780,000 (Direct Cost: ¥10,600,000、Indirect Cost: ¥3,180,000)
|
|---|
| Outline of Final Research Achievements |
In this study, we have developed various supramolecular sensing and separation systems for constructing a more efficient ion and molecule recognition. These systems are based on a combination of various molecular probes with cyclodextrins possessing nano-size cavities by using inclusion complex formation and weak intermolecular interactions. In the combination of ditopic azoprobes with cyclodextrins, the novel supramolecular chirality based on twisted structure of two probes inside cyclodextrin cavity was found to be induced only in the presence of specific metal ions and anions. Furthermore by employing these molecular recognition sites on various nanoparticles such as silica nanoparticle and dendrimers, novel bacteria detection systems have been successfully developed.
|
