New approach to control gastroenteritis viruses in wastewater reclamation and reuse by taking advantage of glycomics information
| Project/Area Number |
26249075
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Civil and environmental engineering
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| Research Institution | Hokkaido University |
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Principal Investigator |
Sano Daisuke 北海道大学, 工学研究院, 准教授 (80550368)
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| Co-Investigator(Kenkyū-buntansha) |
大村 達夫 東北大学, 学内共同利用施設等, 教授 (30111248)
中込 治 長崎大学, 医歯(薬)学総合研究科, 教授 (70143047)
木村 克輝 北海道大学, 工学(系)研究科(研究院), 准教授 (10292054)
加藤 毅 群馬大学, その他部局等, 准教授 (40401236)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥41,860,000 (Direct Cost: ¥32,200,000、Indirect Cost: ¥9,660,000)
Fiscal Year 2016: ¥10,140,000 (Direct Cost: ¥7,800,000、Indirect Cost: ¥2,340,000)
Fiscal Year 2015: ¥11,180,000 (Direct Cost: ¥8,600,000、Indirect Cost: ¥2,580,000)
Fiscal Year 2014: ¥20,540,000 (Direct Cost: ¥15,800,000、Indirect Cost: ¥4,740,000)
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| Keywords | 胃腸炎ウイルス / ノロウイルス / 糖鎖 / 相互作用 / ノロウイルス吸着性細菌 / 膜分離 / ロタウイルス / グライコミクス / レクチン / 下水処理水再生 / マイクロアレイ |
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| Outline of Final Research Achievements |
This study aims to find a new approach to control gastroenteritis viruses in wastewater treatment processes by taking advantage of glycan-recognition of viruses. Firstly, glycans that can be captured by norovirus particles were identified by glycan microarray. Based on the glycan microarray results, GD1a positive bacteria were isolated from environmental water samples. Microfiltration of norovirus in the presence of HBGA-positive bacteria was then performed. HBGA-producing genes were identified to track HBGA-positive bacteria in wastewater treatment processes. Finally, the removal of rotavirus HAL1166, which and recognize HBGA, with microfiltration membrane was investigated.
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Report
(4 results)
Research Products
(35 results)
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[Presentation] 下水再生処理におけるヒト腸管系ウイルスの目標除去効率の算定法2016
Author(s)
伊藤寿宏, 押木守, 小林直央, 加藤毅, 瀬川高弘, 幡本将史, 山口隆司, 原田秀樹, 北島正章, 岡部聡, 佐野大輔
Organizer
第53回環境工学研究フォーラム
Place of Presentation
北九州国際会議場（北九州市）
Year and Date
2016-12-06
Related Report
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