| Budget Amount *help |
¥39,780,000 (Direct Cost: ¥30,600,000、Indirect Cost: ¥9,180,000)
Fiscal Year 2018: ¥6,630,000 (Direct Cost: ¥5,100,000、Indirect Cost: ¥1,530,000)
Fiscal Year 2017: ¥6,630,000 (Direct Cost: ¥5,100,000、Indirect Cost: ¥1,530,000)
Fiscal Year 2016: ¥6,630,000 (Direct Cost: ¥5,100,000、Indirect Cost: ¥1,530,000)
Fiscal Year 2015: ¥10,530,000 (Direct Cost: ¥8,100,000、Indirect Cost: ¥2,430,000)
Fiscal Year 2014: ¥9,360,000 (Direct Cost: ¥7,200,000、Indirect Cost: ¥2,160,000)
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| Outline of Final Research Achievements |
Neuronal transmission from the basal ganglia to thalamocortical projection neurons was examined. First, virus vectors carrying halorhodopsin, which suppresses neuronal activity during yellow light illumination, were injected into the internal segment of the globus pallidus of Japanese monkeys. Then, the optrode made of combination of a metal electrode and a fiber optics was introduced into the thalamus, and thalamic neuronal activity was recorded. We found that movement-related increase of thalamic activity during task performance was greatly diminished by yellow laser light illumination. These results suggest that basal ganglia-thalamocortical neurotransmission is mediated by rebound excitation after inhibition.
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