Study on enteroendocrine, nervous and reproductive systems related to diet for preventing metabolic diseases.
| Project/Area Number |
26252016
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (A)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Food science
|
|---|
| Research Institution | Hokkaido University |
|---|
Principal Investigator |
Hara Hiroshi 北海道大学, 農学研究院, 教授 (70198894)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
比良 徹 北海道大学, (連合)農学研究科(研究院), 講師 (10396301)
|
|---|
| Project Period (FY) |
2014-04-01 – 2017-03-31
|
| Project Status |
Completed (Fiscal Year 2016)
|
| Budget Amount *help |
¥39,780,000 (Direct Cost: ¥30,600,000、Indirect Cost: ¥9,180,000)
Fiscal Year 2016: ¥10,790,000 (Direct Cost: ¥8,300,000、Indirect Cost: ¥2,490,000)
Fiscal Year 2015: ¥10,400,000 (Direct Cost: ¥8,000,000、Indirect Cost: ¥2,400,000)
Fiscal Year 2014: ¥18,590,000 (Direct Cost: ¥14,300,000、Indirect Cost: ¥4,290,000)
|
|---|
| Keywords | 消化管内分泌系 / 食事組成 / GLP-1 / 消化管ホルモン |
|---|
| Outline of Final Research Achievements |
In this project, we investigated gut hormone secretory responses to ‘meal’in the conscious animal model equipped with portal cannula. We have found that gut hormone responses (such as GLP-1, GIP,PYY, Ghrelin) are modified by changing the source of dietary proteins. Furthermore, the effect of dietary protein was modified by the source of carbohydrates in the meal.
Feeding the diet supplemented with resistant maltodextrin which has GLP-1-releasing activity prevented excess energy intake induced by high fat high sucrose diet.
Our results suggest that postprandial gut hormone responses can be desirably manipulated by changing the composition of a meal.
|
Report
(4 results)
Research Products
(11 results)
-
-
-
-
-
-
-
-
[Presentation] 血糖調節ペプチド2016
Author(s)
比良 徹、原 博
Organizer
日本農芸化学会2015年度大会
Place of Presentation
札幌コンベンションセンター（北海道・札幌市）
Year and Date
2016-03-28
Related Report
Invited
-
-
-
