| Budget Amount *help |
¥39,780,000 (Direct Cost: ¥30,600,000、Indirect Cost: ¥9,180,000)
Fiscal Year 2016: ¥10,790,000 (Direct Cost: ¥8,300,000、Indirect Cost: ¥2,490,000)
Fiscal Year 2015: ¥10,400,000 (Direct Cost: ¥8,000,000、Indirect Cost: ¥2,400,000)
Fiscal Year 2014: ¥18,590,000 (Direct Cost: ¥14,300,000、Indirect Cost: ¥4,290,000)
|
|---|
| Outline of Final Research Achievements |
In this project, we investigated gut hormone secretory responses to ‘meal’in the conscious animal model equipped with portal cannula. We have found that gut hormone responses (such as GLP-1, GIP,PYY, Ghrelin) are modified by changing the source of dietary proteins. Furthermore, the effect of dietary protein was modified by the source of carbohydrates in the meal.
Feeding the diet supplemented with resistant maltodextrin which has GLP-1-releasing activity prevented excess energy intake induced by high fat high sucrose diet.
Our results suggest that postprandial gut hormone responses can be desirably manipulated by changing the composition of a meal.
|
