Elucidation of neural mechanisms of emotion generation and emotion regulation in the social brain with HD-DOT and fMRI
| Project/Area Number |
26280050
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Cognitive science
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| Research Institution | Hamamatsu University School of Medicine (2015-2017)
Tokyo Metropolitan Institute of Medical Science (2014) |
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Principal Investigator |
Hoshi Yoko 浜松医科大学, 光尖端医学教育研究センター, 教授 (50332383)
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| Co-Investigator(Kenkyū-buntansha) |
精山 明敏 京都大学, 医学研究科, 教授 (70206605)
谷川 ゆかり 国立研究開発法人産業技術総合研究所, 情報・人間工学領域, 研究グループ長 (20344202)
川口 拓之 国立研究開発法人産業技術総合研究所, 情報・人間工学領域, 研究員 (60510394)
榛葉 俊一 公益財団法人東京都医学総合研究所, 認知症・高次脳機能研究分野, 研究員 (80175398)
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| Research Collaborator |
KOHNO Satoru
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| Project Period (FY) |
2014-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥16,120,000 (Direct Cost: ¥12,400,000、Indirect Cost: ¥3,720,000)
Fiscal Year 2016: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2015: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2014: ¥7,410,000 (Direct Cost: ¥5,700,000、Indirect Cost: ¥1,710,000)
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| Keywords | 感情制御 / 神経メカニズム / 拡散光トモグラフィ / 対人関係 / 社会脳 / 感情 / ヘモグロビン / 皮膚血流 / NIRS / 脳・神経 / 認知科学 / 行動学 / 生理学 / 情動 / DOT / 近赤外線スペクトロスコピー |
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| Outline of Final Research Achievements |
The social brain refers to brain functions that are required for social interactions, such as reading between the lines and being patient. Social interactions often elicit emotions, and emotion regulation is involved in the social brain. Various mental disorders are thought to be attributed to social brain dysfunctions, whereas neural mechanisms of the social brain remain to be elucidated. Near-infrared spectroscopy (NIRS) is a useful approach to emotion studies; however, NIRS signals are inherently subjected to contamination by signals arising from extracerebral tissue, mainly skin blood flows. The present study with functional magnetic resonance imaging (fMRI) revealed the neural mechanisms behind generation and regulation of negative emotions in interpersonal relationships. In addition, to overcome the issue of skin blood flow contaminations, we developed the high-density diffuse optical tomography (HD-DOT).
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Report
(5 results)
Research Products
(67 results)
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[Journal Article] Roadmap on neurophotonics.2016
Author(s)
Cho YK, Zheng G, Augustine GJ, Hochbaum D, Cohen A, Knöpfel T, Pisanello F, Pavone FS, Vellekoop IM, Booth MJ, Hu S, Zhu J, Chen Z, Hoshi Y
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Journal Title
J. Opt.
Volume: 18
Issue: 9
Pages: 093007-093007
DOI
Related Report
Peer Reviewed / Int'l Joint Research
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[Journal Article] fMRI evidence of improved visual function in patients with progressive retinitis pigmentosa by eye-movement training.2014
Author(s)
Yoshida M, Origuchi M, S, Takatsuki A, Kan S, Aso T, Shiose T, Sawamoto S, Miyauchi S, Fukuyama H, Seiyama A.
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Journal Title
NeuroImage: Clin.
Volume: 5
Pages: 161-168
DOI
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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[Presentation] Non-contact scanning time-domain functional optical imaging of adult human brain.2015
Author(s)
Wabnitz H, Mazurenaka M, Fucks K. Di Sieno L, Boso G, Contini D, Mora AD, Tosi A, Hoshi Y, Pifferi A, Macdonald R.
Organizer
ECBO 2015
Place of Presentation
Messe Munchen, Munich, Germany
Year and Date
2015-06-21
Related Report
Int'l Joint Research / Invited
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[Presentation] Diffuse optical tomography: how to improve image quality?2015
Author(s)
Hoshi Y, Okada E, Okawa S, Tanikawa Y, Yoshinaga T, Fujii H, Fujimoto K, Hashimoto K, Kohno S.
Organizer
ICM 2015
Place of Presentation
Okayama convention center, Okayama, Japan
Year and Date
2015-06-18
Related Report
Int'l Joint Research / Invited
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[Presentation] Development of time-domain diffuse optical tomography based on a radiative transfer equation and diffusion approximation hybrid.2014
Author(s)
3.Hoshi Y, Okada E, Okawa S, Tanikawa Y, Yoshinaga T, Fujii H, Fujimoto K, Hashimoto K, Kohno S.
Organizer
fNIRS2014
Place of Presentation
University of Montreal, Montreal, Canada
Year and Date
2014-10-10 – 2014-10-12
Related Report
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