| Project/Area Number |
26282141
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Medical systems
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| Research Institution | Akita University |
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Principal Investigator |
Shimizu Hiroaki 秋田大学, 医学(系)研究科(研究院), 教授 (20506638)
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| Co-Investigator(Kenkyū-buntansha) |
冨永 悌二 東北大学, 医学(系)研究科(研究院), 教授 (00217548)
新妻 邦泰 東北大学, その他の研究科, 助教 (10643330)
杉山 慎一郎 東北大学, 医学(系)研究科(研究院), その他 (30623152)
鷲尾 利克 国立研究開発法人産業技術総合研究所, その他部局等, 研究員 (40358370)
大田 英揮 東北大学, 大学病院, 助教 (40586905)
荒船 龍彦 東京電機大学, 理工学部, 助教 (50376597)
船本 健一 東北大学, 学内共同利用施設等, 准教授 (70451630)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥16,640,000 (Direct Cost: ¥12,800,000、Indirect Cost: ¥3,840,000)
Fiscal Year 2016: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2015: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2014: ¥8,320,000 (Direct Cost: ¥6,400,000、Indirect Cost: ¥1,920,000)
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| Keywords | 脳動静脈奇形 / 数値流体力学 / 集学的治療 / 脳動脈瘤 / MRI / 脳血管撮影 / 数値流体解析 / 脳神経外科学 / 脳血管障害学 |
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| Outline of Final Research Achievements |
Hemodynamics of arteriovenous malformation (AVM) was successfully analyzed using computational fluid dynamics (CFD). Four dimensional magnetic resonance imaging (4D-MRI) was also performed and compared with CFD. Hemodynamic parameters such as wall shear stress and velocity were provide by both CFD and 4D-MRI. However patients who suffered from AVM mostly had severe physical conditions, and it was difficult to create a large database during three years.
On the other hand, the research team developed a new approach for diagnosing the risk factor of the recurrence after coil embolization of cerebral aneurysms. Based on it, a new software to evaluate the risk for coil embolization is under developing. In conclusion, this project became a foundation for the future development of CFD.
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