| Project/Area Number |
26282150
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Medical systems
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| Research Institution | Nihon University (2015-2016)
National Research Institute for Child Health and Development (2014) |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
梅村 晋一郎 東北大学, その他の研究科, 教授 (20402787)
宮本 義孝 国立研究開発法人国立成育医療研究センター, その他部局等, 研究員 (20425705)
土岐 彰 昭和大学, 医学部, 教授 (50163960)
千葉 敏雄 日本大学, 総合科学研究所, 教授 (20171944)
杉山 彰英 昭和大学, 医学部, 講師 (10349087)
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| Research Collaborator |
SOBHAN Ubaidus
MOCHIZUKI Takashi
OSAWA Shunsuke
ANDO Shinsuke
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥16,510,000 (Direct Cost: ¥12,700,000、Indirect Cost: ¥3,810,000)
Fiscal Year 2016: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2015: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2014: ¥7,020,000 (Direct Cost: ¥5,400,000、Indirect Cost: ¥1,620,000)
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| Keywords | 集束超音波 / 医療・福祉 / 胎児治療 / 超音波画像 |
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| Outline of Final Research Achievements |
This study aims development of basic technologies for medical application of the high intensity focused ultrasound (HIFU) for minimal invasive before-birth fetal therapy, especially for therapy of congenital diaphragmatic hernia. We invented a new method to release a balloon, in fetal trachea by easy delivery of HIFU. We confirmed that balloon was inflated by nano-droplet or micro-capsuled limonene and wall of the balloon was broken or perforated only by HIFU-delivery with high probability in phantom and in vitro animal experiments.
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