Renal Rehabilitation: Promotion of research for the guidelines on the practical application of new device for patients with CKD
| Project/Area Number |
26282153
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | Tohoku University |
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Principal Investigator |
Masahiro KOHZUKI 東北大学, 医学(系)研究科(研究院), 教授 (70234698)
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| Co-Investigator(Kenkyū-buntansha) |
伊藤 修 東北大学, 医学(系)研究科(研究院), 准教授 (00361072)
森 信芳 東北大学, 医学(系)研究科(研究院), 助教 (50463790)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥16,250,000 (Direct Cost: ¥12,500,000、Indirect Cost: ¥3,750,000)
Fiscal Year 2016: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2015: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2014: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
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| Keywords | リハビリテーション / 慢性腎臓病 / ガイドライン作成 / 開発機器 / 効果の検証 / 機序解明 / 酸化ストレス / 循環器・高血圧 / 腎臓 / 組織・細胞 / 循環器・高血圧・高血圧 / 医療・福祉・福祉 / 細胞・組織・組織 |
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| Outline of Final Research Achievements |
Chronic kidney disease (CKD) is a worldwide public health problem. Renal rehabilitation (RR) is coordinated, multifaceted interventions designed to optimize a renal patient's physical, psychological, and social functioning, in addition to stabilizing, slowing, or even reversing the progression of renal deterioration, thereby reducing morbidity and mortality. RR includes five major components: such as exercise training, diet & fluid management, medication & medical surveillance, education, psychological & vocational counseling. In this study, we investigated the effects of the exercise therapy in the basic medical science and clinical medical science about the renal rehabilitation. Furthermore, we have developed the device (TE2-20) in cooperation with private companies for developing the kidney rehabilitation exercise therapy guidelines.
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Report
(4 results)
Research Products
(92 results)
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[Journal Article] Water Deprivation Increases (Pro)renin Receptor Levels in the Kidney and Decreases Plasma Concentrations of Soluble (Pro)renin Receptor2016
Author(s)
Tamura Y, Mori N, Xu B, Nakamaura T, Yamakoshi S, Hirose T, Ito O, Totsune K, Takahashi K, Kohzuki M.
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Journal Title
The Tohoku Journal of Experimental Medicine
Volume: 239
Issue: 3
Pages: 185-192
DOI
NAID
ISSN
0040-8727, 1349-3329
Related Report
Peer Reviewed / Open Access
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[Journal Article] Chronic Running Exercise Alleviates Early Progression of Nephropathy with Upregulation of Nitric Oxide Synthases and Suppression of Glycation in Zucker Diabetic Rats2015
Author(s)
Ito D, Cao P, Kakihana T, Sato E, Suda C, Muroya Y, Ogawa Y, Hu G, Ishii T, Ito O, Kohzuki M, Kiyomoto H
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Journal Title
PLoS One
Volume: 10
Issue: 9
Pages: 0138037-0138037
DOI
Related Report
Peer Reviewed / Open Access
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[Presentation] The expression of (pro)renin receptor is upregulated in the kidney of Dahl salt-sensitive rats by high salt intake.2016
Author(s)
Yamakoshi S, Ito O, Rong R, Osaki Y, Muroya Y, Mori T, Ito S, Takahashi K, Totsune K, Kohzuki M.
Organizer
ISH 2016 satellite symposium, Renin-angiotensin-aldosterone system (RAAS)
Place of Presentation
Tokyo(congres square Nihonbashi)
Year and Date
2016-09-23
Related Report
Int'l Joint Research
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[Presentation] 腎臓リハビリテーション.2016
Author(s)
上月正博, 伊藤 修.
Organizer
第53回日本リハビリテーション医学会
Place of Presentation
国立京都会議場(京都市・京都府)
Year and Date
2016-06-09
Related Report
Invited
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[Presentation] Pitavastatin has antihypertensive and renoprotective effects with upregulation of NO system and down-regulation of oxidative stress in the kidney of spontaneously hypertensive rats.2016
Author(s)
Hu G, Ito O, Rong R, Xu B, Sakuyama A, Miura A, Ogawa Y, Ito D, Kohzuki M.
Organizer
International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide
Place of Presentation
Sendai(Sendai international center)
Year and Date
2016-05-20
Related Report
Int'l Joint Research
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