Budget Amount *help |
¥15,600,000 (Direct Cost: ¥12,000,000、Indirect Cost: ¥3,600,000)
Fiscal Year 2016: ¥5,980,000 (Direct Cost: ¥4,600,000、Indirect Cost: ¥1,380,000)
Fiscal Year 2015: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2014: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
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Outline of Final Research Achievements |
Cell, scaffold, and nutrition are the three essential elements of regenerative medicine. However, these elements focus only on cells or tissues, but not organs and individuals. The purpose of this study was to develop and show the usefulness of rehabilitation resource to promote the regenerative effect of regenerative medicine. The osteochondral defect on rat knee joint was additively regenerated by mesenchymal stromal cell transplantation when combined with exercise or low-intensity pulsed ultrasonographic stimulation. These data suggest that rehabilitation programs can be the fourth element to promote the effect of regenerative medicine.
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