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Modulatory effects of postnatal experience on rat hippocampal local field potentials

Research Project

Project/Area Number 26282222
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypePartial Multi-year Fund
Section一般
Research Field Brain biometrics
Research InstitutionInstitute of Physical and Chemical Research

Principal Investigator

Shinohara Yoshiaki  国立研究開発法人理化学研究所, 脳科学総合研究センター, 研究員 (10425423)

Co-Investigator(Kenkyū-buntansha) 遠藤 整  東海大学, 医学部, 講師 (10550551)
田嶋 敦  金沢大学, 医学系, 教授 (10396864)
Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥17,160,000 (Direct Cost: ¥13,200,000、Indirect Cost: ¥3,960,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2014: ¥11,960,000 (Direct Cost: ¥9,200,000、Indirect Cost: ¥2,760,000)
Keywords海馬 / 脳波 / 脳の左右差 / 生後環境 / in vivo / 左右差 / 豊かな環境 / 環境 / γ波 / 生理学
Outline of Final Research Achievements

Postnatal environmental experience has significant effects on brain development. We reported that rat reared in enriched environment after weaning exbibits greater magnitudes and increased synchronized activities of hippocampal gamma oscillations than rats reared in isolated conditions. We found in longer periods, gamma oscillations and synchrony mature also in isolated rats, but much slower than those reared in enriched environment. Moreover, we found that astrocytic spontaneous calcium oscillations have modulatory effects on hippocampal local field potentials in environment-dependent manner.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Annual Research Report
  • 2014 Annual Research Report
  • Research Products

    (13 results)

All 2017 2016 2015 2014 Other

All Journal Article (4 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 4 results,  Open Access: 2 results,  Acknowledgement Compliant: 3 results) Presentation (8 results) (of which Int'l Joint Research: 4 results,  Invited: 4 results) Remarks (1 results)

  • [Journal Article] Network mechanisms of hippocampal laterality, place coding, and goal-directed navigation.2017

    • Author(s)
      Kitanishi,T., Ito,H.T., Hayashi,Y., Shinohara,Y., Mizuseki,K., Hikida,T.
    • Journal Title

      J. Physiol Sci.

      Volume: 67 Issue: 2 Pages: 247-258

    • DOI

      10.1007/s12576-016-0502-z

    • NAID

      40021113908

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Adaptive changes of extracellular amino acid concentrations in mouse dorsal striatum by 4-AP-induced cortical seizures2015

    • Author(s)
      Terumi Nagai, Norio Takata, Yoshiaki Shinohara, Hajime Hirase
    • Journal Title

      Neuroscience

      Volume: 295 Pages: 229-236

    • DOI

      10.1016/j.neuroscience.2015.03.043

    • NAID

      120006386964

    • Related Report
      2015 Annual Research Report 2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Transformation of cortical and hippocampal neural circuit by environmental enrichment.2014

    • Author(s)
      Hirase, H, Shinohara Y.
    • Journal Title

      Neuroscience

      Volume: 280 Pages: 282-298

    • DOI

      10.1016/j.neuroscience.2014.09.031

    • NAID

      120006386962

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Volume transmission signalling via astrocytes.2014

    • Author(s)
      Hirase H, Iwai Y, Takata N, AShinohara Y Mishima T
    • Journal Title

      Philos Trans R Soc Lond B Biol Sci.

      Volume: 369 Issue: 1654 Pages: 20130604-20130604

    • DOI

      10.1098/rstb.2013.0604

    • NAID

      120006386963

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] “Cooperation and specialization of the bilateral hippocampi in rodents.”2016

    • Author(s)
      Shinohara Y
    • Organizer
      日本生理学大会
    • Place of Presentation
      札幌コンベンションセンター(札幌)
    • Year and Date
      2016-03-22
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] “Experience drives development of left-right asymmetrical gamma oscillations in rat hippocampus”2016

    • Author(s)
      Yoshiaki Shinohara
    • Organizer
      日本神経科学会大会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Cooperation and specialization of the bilateral hippocampi in rodents2015

    • Author(s)
      Y. SHINOHARA, A. HOSOYA, H. HIRASE
    • Organizer
      Society for Neuroscience
    • Place of Presentation
      Chicago
    • Year and Date
      2015-10-17
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Left-right asymmetrical development of hippocampal gamma oscillations by animal experience2015

    • Author(s)
      Shinohara Y, Hosoya A, Hirase H
    • Organizer
      日本神経科学大会
    • Place of Presentation
      神戸国際会議場・神戸国際展示場(神戸)
    • Year and Date
      2015-07-27
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Ultrastructural investigation of lateralized experience-dependent synaptic plasticity in rat hippocampal CA1 stratum radiatum2014

    • Author(s)
      Shinohara Y, Hosoya A, Hirase H
    • Organizer
      日本神経科学会
    • Place of Presentation
      パシフィコ横浜・神奈川県横浜市
    • Year and Date
      2014-09-11 – 2014-09-13
    • Related Report
      2014 Annual Research Report
  • [Presentation] Cooperation and specialization of the bilateral hippocampi in rodents2014

    • Author(s)
      Shinohara Y
    • Organizer
      筑波大学国際統合睡眠化学研究所
    • Place of Presentation
      国際統合睡眠医科学研究機構・茨城県つくば市
    • Year and Date
      2014-07-22
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Ultrastructural investigation of lateralized experience-dependent synaptic plasticity in rat hippocampal CA1 stratum radiatum2014

    • Author(s)
      Shinohara Y, Hosoya A, Hirase H
    • Organizer
      FENS
    • Place of Presentation
      Milan, Italy
    • Year and Date
      2014-07-05 – 2014-07-09
    • Related Report
      2014 Annual Research Report
  • [Presentation] Cooperation and specialization of the bilateral hippocampi in rodents2014

    • Author(s)
      Shinohara Y
    • Organizer
      Kavli Institute for System Neuroscience
    • Place of Presentation
      Trondheim, Norway
    • Year and Date
      2014-07-03
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Remarks] http://ngc.brain.riken.jp/research.html

    • Related Report
      2014 Annual Research Report

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Published: 2014-04-04   Modified: 2018-03-22  

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