Analysis of signal path of reactions between model cells and quantified radicals
Project/Area Number |
26286072
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Research Category |
Grant-in-Aid for Scientific Research (B)
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Allocation Type | Partial Multi-year Fund |
Section | 一般 |
Research Field |
Plasma electronics
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Research Institution | Meijo University |
Principal Investigator |
Ito Masafumi 名城大学, 理工学部, 教授 (10232472)
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Co-Investigator(Kenkyū-buntansha) |
竹田 圭吾 名古屋大学, 工学(系)研究科(研究院), 助教 (00377863)
太田 貴之 名城大学, 理工学部, 准教授 (10379612)
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Project Period (FY) |
2014-04-01 – 2017-03-31
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Project Status |
Completed (Fiscal Year 2016)
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Budget Amount *help |
¥15,860,000 (Direct Cost: ¥12,200,000、Indirect Cost: ¥3,660,000)
Fiscal Year 2016: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2014: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
|
Keywords | 低温プラズマ / プラズマ理工学 / 農学応用 / 薬学応用 / 酸素ラジカル / 酸化窒素ラジカル / 酸素原子 / 一酸化窒素 / ラジカル / NOx |
Outline of Final Research Achievements |
In this study, we have quantitatively clarified the doses of radicals for activating, suppressing, inactivating spores, bacteria, or cells in the atmosphere or solutions. Besides, we have almost elucidated the mechanisms of activation and inactivation of cells and so on from the quantitative results of intracellular structural changes and of the concentrations of hydrogen peroxide, hypochlorous acid, and nitrate ions generated in the solutions irradiated with radicals using various spectroscopies. Furthermore, as for cultured animal cells, we have almost clarified the signal path of selective inactivation using melanoma and mouse fibroblast cells.
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Report
(4 results)
Research Products
(94 results)
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[Journal Article] How plasma induced oxidation, oxygenation, and de-oxygenation influences viability of skin cells2016
Author(s)
J.-S. Oh, X. Strudwick, R. D. Short, K. Ogawa, A. Hatta, H. Furuta, N. Gaur, S.-H. Hong, A. J. Cowin, H. Fukuhara, K. Inoue, M. Ito, C. Charles, R. W. Boswell, J. W. Bradley, D. B. Graves and E. J. Szili
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Journal Title
Applied Physics Letters
Volume: 109
Issue: 20
Pages: 2037011-5
DOI
Related Report
Peer Reviewed / Int'l Joint Research
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[Presentation] Inactivation Mechanism of E. coli in Liquids Using Oxygen Radical Source2017
Author(s)
T. Kobayashi, J. Oh, H. Hashizume, T. Ohta, K. Ishikawa, M. Hori, M. Ito
Organizer
Taiwan- Japan Joint Workshop of 5th International Workshop for Nano-Carbon Workshop (IWNC) and 7th International Workshop for Plasma-bio Science and Technology (IWPBST)
Place of Presentation
Nagoya Dome-Mae Campus, Meijo University, Nagoya
Year and Date
2017-03-06
Related Report
Int'l Joint Research
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[Presentation] Measurement of reactive oxygen/nitrogen species in plasma-treated water2017
Author(s)
K. Yamamasu, K. Yamashita, T. Ohta, M. Ito, M. Hori
Organizer
Taiwan- Japan Joint Workshop of 5th International Workshop for Nano-Carbon Workshop (IWNC) and 7th International Workshop for Plasma-bio Science and Technology (IWPBST)
Place of Presentation
Nagoya Dome-Mae Campus, Meijo University, Nagoya
Year and Date
2017-03-06
Related Report
Int'l Joint Research
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[Presentation] Dependence of mold spores on oxidative stress through oxygen atoms2017
Author(s)
Y. Tanaka, H. Hashizume, J. Oh, K. Ishikawa, T. Ohta, M. Hori, and M. Ito
Organizer
9th International Symposium on Advanced Plasma Science and its Applications for Nitrides and Nanomaterials/10th International Conference on Plasma-Nano Technology & Science
Place of Presentation
Chubu University, Kasugai, Aichi
Year and Date
2017-03-01
Related Report
Int'l Joint Research
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[Presentation] Interaction of Plasma with Cells for Agriculture and Biomedical Applications2017
Author(s)
M. Hori, M. Sekine, K. Ishikawa, H. Kondo, K. Takeda, H. Hashizume, H. Tanaka, F. Kikkawa, M. Mizuno and M. Ito
Organizer
3rd International Workshop on Advanced Plasma Technology and Applications
Place of Presentation
Nong Lam University, Hochiminh, Vietnam
Year and Date
2017-01-11
Related Report
Int'l Joint Research / Invited
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[Presentation] Bioscience and applications using plasmas2016
Author(s)
M. Ito
Organizer
Taiwan-Japan Joint Workshop of 4th International Work shop for Nano-Carbon and Workshop and 6th International Workshop for Plasma-bio Science and Technology
Place of Presentation
Chung-Yuan Christian University and National Taiwan University of Science & Technology, Taiwan
Year and Date
2016-11-03
Related Report
Int'l Joint Research
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[Presentation] Oxygen radical reactions in liquid phase for inactivating microorganisms2016
Author(s)
T. Kobayashi, J.-S. Oh, H. Hashizume, T. Ohta, K. Ishikawa, M. Hori, M. Ito
Organizer
Taiwan-Japan Joint Workshop of 4th International Work shop for Nano-Carbon and Workshop and 6th International Workshop for Plasma-bio Science and Technology
Place of Presentation
Chung-Yuan Christian University and National Taiwan University of Science & Technology, Taiwan
Year and Date
2016-11-03
Related Report
Int'l Joint Research
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[Presentation] Proliferative effects of nitric oxide irradiation on budding yeast cells2016
Author(s)
M. Okachi, J.-S. Oh, H. Hashizume, M. Hori, M. Ito
Organizer
Taiwan-Japan Joint Workshop of 4th International Work shop for Nano-Carbon and Workshop and 6th International Workshop for Plasma-bio Science and Technology
Place of Presentation
Chung-Yuan Christian University and National Taiwan University of Science & Technology, Taiwan
Year and Date
2016-11-03
Related Report
Int'l Joint Research
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[Presentation] Apoptosis pass of melanoma cells in medium irradiated by oxygen radicals2016
Author(s)
T. Koizumi, T. Murata, M. Hori, M. Ito
Organizer
Taiwan-Japan Joint Workshop of 4th International Work shop for Nano-Carbon and Workshop and 6th International Workshop for Plasma-bio Science and Technology
Place of Presentation
Chung-Yuan Christian University and National Taiwan University of Science & Technology, Taiwan
Year and Date
2016-11-03
Related Report
Int'l Joint Research
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[Presentation] Cell response of fungi spores to oxygen radical irradiation2016
Author(s)
Y. Tanaka, H. Hashizume, J.-S. Oh, T. Ohta, M. Hori, M. Ito
Organizer
Taiwan-Japan Joint Workshop of 4th International Work shop for Nano-Carbon and Workshop and 6th International Workshop for Plasma-bio Science and Technology
Place of Presentation
Chung-Yuan Christian University and National Taiwan University of Science & Technology, Taiwan
Year and Date
2016-11-03
Related Report
Int'l Joint Research
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[Presentation] Dynamic behavior of HeLa Cells in plasma-activated medium2016
Author(s)
R. Furuta, H. Hashizume, K. Ishikawa, H. Tanaka, K. Takeda, T. Ohta, H. Kondo, M. Ito, M. Sekine, M. Hori
Organizer
6th International Conference on Plasma Medicine
Place of Presentation
Bratislava, Slovakia
Year and Date
2016-09-04
Related Report
Int'l Joint Research
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[Presentation] Molecular Vibrational Imaging of Plasma-Induced Biological Samples2016
Author(s)
R. Furuta, H. Hashizume, K. Ishikawa, H. Tanaka, K. Takeda, T. Ohta, H. Kondo, M. Ito, M. Sekine, M. Hori
Organizer
7th International Workshop on Plasma Spectroscopy
Place of Presentation
Inuyama, Aichi
Year and Date
2016-06-26
Related Report
Int'l Joint Research
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[Presentation] Inactivation effects of neutral-pH solutions treated with oxygen radicals2015
Author(s)
T. Kobayashi, T. Ohta, H. Hashizume, K. Ishikawa, M. Hori, M. Ito
Organizer
Joint Symposium of the 9th Asia-Pacific International Symposium on the Basics and Applications of Plasma Technology and the 28th Symposium on Plasma Science for Materials(APSPT-9/SPSM-28)
Place of Presentation
Nagasaki University
Year and Date
2015-12-12
Related Report
Int'l Joint Research
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