Anisotropic function of antifreeze protein for ice crystal growth - To elucidate growth promotion and inhibition mechanism
| Project/Area Number |
26287095
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (B)
|
| Allocation Type | Partial Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Biological physics/Chemical physics/Soft matter physics
|
|---|
| Research Institution | Hokkaido University |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
佐崎 元 北海道大学, 低温科学研究所, 教授 (60261509)
長嶋 剣 北海道大学, 低温科学研究所, 助教 (60436079)
村田 憲一郎 北海道大学, 低温科学研究所, 助教 (60646272)
|
|---|
| Project Period (FY) |
2014-04-01 – 2018-03-31
|
| Project Status |
Completed (Fiscal Year 2017)
|
| Budget Amount *help |
¥16,900,000 (Direct Cost: ¥13,000,000、Indirect Cost: ¥3,900,000)
Fiscal Year 2016: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2015: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2014: ¥8,190,000 (Direct Cost: ¥6,300,000、Indirect Cost: ¥1,890,000)
|
|---|
| Keywords | 氷結晶 / 不凍タンパク質 / 界面吸着 / 結晶成長 / 異方的不純物効果 / 振動成長 / 成長速度促進 / 凍結抑制タンパク質 / 不純物効果 / 成長促進 / 成長速度の促進 / 成長速度の振動 / 界面カイネティクス / 生体高分子 / 反射型干渉顕微鏡 / 固液界面 |
|---|
| Outline of Final Research Achievements |
Growth experiments of an ice crystal in a supercooled solution of antifreeze protein were carried out and separately measured the growth rates for the basal and prism faces. We clarified that the growth of basal faces was enhanced by the effect of antifreeze protein, while the growth of prism faces was suppressed. It means that the effects of antifreeze proteins for ice crystal growth were different for every crystallographic faces.
The growth promotion of basal face was explained by a new model that the adsorbed antifreeze protein molecules on the edges of growth steps may work as the new sources to generate new growth steps on the basal faces. We clarified that the mechanism for the freezing inhibition of living organisms under the sub-zero temperature environments was compatibly explained on the basis of the anisotropic functions of antifreeze proteins for ice crystal growth.
|
Report
(5 results)
Research Products
(33 results)
-
-
-
-
-
[Journal Article] Oscillations and accelerations of ice crystal growth rates in microgravity in presence of antifreeze glycoprotein impurity in supercooled water2017
Author(s)
Yoshinori Furukawa, Ken Nagashima, Shun-ichi Nakatsubo, Izumi Yoshizaki, Haruka Tamaru, Taro Shimaoka, Takehiko Sone, Etsuro Yokoyama, Salvador Zepeda, Takanori Terasawa, Harutoshi Asakawa, Ken-ichiro Murata and Gen Sazaki
-
Journal Title
Scientific Reports
Volume: 7
Issue: 1
Pages: 43157-43157
DOI
NAID
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
-
-
-
-
-
-
-
-
[Presentation] Anisotropic impurity effect for ice crystal growth in supercooled water2018
Author(s)
FURUKAWA, Yoshinori, NAGASHIMA, Ken, NAKATSUBO, Shun-ichi, MURATA, Ken-ichiro, SAZAKI, Gen, ZEPEDA, Salvador, YOKOYAMA, Etsuro
Organizer
14th International Conference on the Physics and Chemistry of Ice (PCI-2018)
Related Report
Int'l Joint Research / Invited
-
-
-
-
-
-
-
-
-
[Presentation] Oscillatory Growth of Ice Crystal Observed in Supercooled Water Containing Antifreeze Glycoprotein2016
Author(s)
Y. Furukawa, K. Nagashima, S. Nakatsubo, H. Tamaru, I. Yoshizaki, T. Shimaoka, T. Sone, E. Yokoyama, T. Maki, A. Yamamoto, H. Asakawa, K. Murata, G. Sazaki
Organizer
The 18th International Conference on Crystal Growth and Epitaxy
Place of Presentation
Nagoya Congress Center, Nagoya
Year and Date
2016-08-07
Related Report
Int'l Joint Research
-
-
-
[Presentation] Oscillatory Growth of Ice Crystal Observed under Microgravity Condition in ISS-Kibo2015
Author(s)
Y. Furukawa, K. Nagashima, S. Nakatsubo, I. Yoshizaki, T. Shimaoka, H. Tamaru, T. Sone, E. Yokoyama, T. Maki, A. Yamamoto
Organizer
The 22nd ELGRA Symposium and General Assembly
Place of Presentation
Corfu Chandres Villa & Hotel, Corfu, Greece
Year and Date
2015-09-29
Related Report
Int'l Joint Research
-
-
-
-
-
-
-
-
