| Budget Amount *help |
¥16,900,000 (Direct Cost: ¥13,000,000、Indirect Cost: ¥3,900,000)
Fiscal Year 2016: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2015: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2014: ¥8,840,000 (Direct Cost: ¥6,800,000、Indirect Cost: ¥2,040,000)
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| Outline of Final Research Achievements |
The principle investigator established an efficient iridium catalyst system for conversion of sterically demanding C(sp3)-H bonds into C(sp3)-B bonds. He also found an iridium-catalyzed addition of C(sp3)-H bond across carbon-carbon multiple bonds, namely hydroalkylation. New insights into α-aminoalkylboron reagents in stereospecific Suzuki-Miyaura coupling, as well as in nucleophilic carbon-carbon bond formation mediated by alkali metal alkoxides, is obtained in the present study. These findings are valuable for rapid production of enantioenriched chiral molecules, which would innovate drug and functional material developments and researches involving chiral recognition.
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