Development of cyclization reaction based on the internal redox reaction which involves C-H activation reaction
| Project/Area Number |
26288053
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (B)
|
| Allocation Type | Partial Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Synthetic chemistry
|
|---|
| Research Institution | Gakushuin University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2014-04-01 – 2018-03-31
|
| Project Status |
Completed (Fiscal Year 2017)
|
| Budget Amount *help |
¥16,640,000 (Direct Cost: ¥12,800,000、Indirect Cost: ¥3,840,000)
Fiscal Year 2016: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2015: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2014: ¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
|
|---|
| Keywords | 有機合成化学 / 選択的反応 / 炭素ー水素結合活性化 / 環化反応 / 触媒反応 / internal redox reaction / C-H結合官能基化 / ヒドリド移動 / 立体選択性 / 炭素―炭素結合生成反応 / 不斉合成反応 / 炭素-炭素結合生成反応 / 触媒 / 炭素ー炭素結合 / 環状化合物 / 炭素ー炭素結合生成反応 |
|---|
| Outline of Final Research Achievements |
Development of efficient synthetic method leading to the biologically active compounds represents one of the important task of organic chemistry.
We are interested in the internal redox reaction which involves [1,5]-H shift and subsequent cyclization reaction to form cyclized product. This internal redox reaction does not require external oxidatant because both reduction and oxidation took place in the molecule. We have developed domino internal reaction and enantioselective version of the domino reaction.
|
Report
(5 results)
Research Products
(14 results)
