| Budget Amount *help |
¥16,770,000 (Direct Cost: ¥12,900,000、Indirect Cost: ¥3,870,000)
Fiscal Year 2016: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2015: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2014: ¥7,150,000 (Direct Cost: ¥5,500,000、Indirect Cost: ¥1,650,000)
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| Outline of Final Research Achievements |
Cell membrane is an essential component of cells and there has been a continuing demand on method to analyze molecular functions on the cell membrane. In this research, we tried to design fluorescent aptamer sensors with a high performance and developed BODIPY dye-labeled fluorescent aptamer sensors that emit an enhanced fluorescence upon interaction with target biomolecule (adenine compound or interferon gamma). In addition, it was demonstrated that these fluorescence aptamer sensors work on cell membrane and can be used for a fluorescent molecular imaging.
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