Elucidation of the posture control disability in cerebellar ataxia from the model-based evaluation of patients and rodents
| Project/Area Number |
26289063
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Intelligent mechanics/Mechanical systems
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| Research Institution | The University of Electro-Communications |
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Principal Investigator |
Funato Tetsuro 電気通信大学, 情報理工学(系)研究科, 助教 (40512869)
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| Co-Investigator(Kenkyū-buntansha) |
柳原 大 東京大学, 総合文化研究科, 准教授 (90252725)
石川 欽也 東京医科歯科大学, 医学部附属病院, 教授 (30313240)
青井 伸也 京都大学, 工学(系)研究科(研究院), 講師 (60432366)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥16,900,000 (Direct Cost: ¥13,000,000、Indirect Cost: ¥3,900,000)
Fiscal Year 2016: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2015: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2014: ¥9,100,000 (Direct Cost: ¥7,000,000、Indirect Cost: ¥2,100,000)
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| Keywords | 姿勢制御 / 小脳疾患 / 力学モデル / 動物モデル |
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| Outline of Final Research Achievements |
In order to elucidate the mechanism that the cerebellar ataxia yielded the posture control disability, this research constructed an evaluation method of posture control system from measured biological data and dynamical model. As a result, 1: dynamical model with variable postural state and its evaluation method, 2: noble standing experiment of rats with bipedal standing were constructed, and through these two methods, the posture disability due to cerebellar ataxia could be evaluated as the change in the control system. By evaluating the standing motion of rats with lesion in inferior olivary nuclei and a patient with cerebellar ataxia, change in the posture control system such that the decreased control torque of rats and decreased integral control of the patient were numerically shown.
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Report
(4 results)
Research Products
(70 results)
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[Presentation] ヒトの歩行・走行遷移時の筋シナジー解析2017
Author(s)
高橋 弘宗, 大島 裕子, 青井 伸也, 舩戸 徹郎, 辻内 伸好, 伊藤 彰人, 土屋 和雄
Organizer
第29回自律分散システム・シンポジウム
Place of Presentation
調布クレストンホテル（東京都調布市）
Year and Date
2017-01-30
Related Report
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[Presentation] ニホンザル二足／四足歩行時の筋シナジー解析2017
Author(s)
大島 裕子, 中陦 克己, 日暮 泰男, 青井 伸也, 舩戸 徹郎, 辻内 伸好, 伊藤 彰人, 土屋 和雄
Organizer
第29回自律分散システム・シンポジウム
Place of Presentation
調布クレストンホテル（東京都調布市）
Year and Date
2017-01-30
Related Report
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[Presentation] Source Separation and Localization of Individual Superficial Forearm Extensor Muscles using High-Density Surface Electromyography2016
Author(s)
Becky Su, Shouhei Shirafuji, Tomomichi Oya, Yousuke Ogata, Tetsuro Funato, Natsue Yoshimura, Luca Pion-Tonachini, Scott Makeig, Kazuhiko Seki, Jun Ota
Organizer
IEEE International symposium on micro-nano mechatronics and human science
Place of Presentation
Nagoya University (Aichi, Nagoya)
Year and Date
2016-11-28
Related Report
Int'l Joint Research
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[Book] Quantification of temporal parameters for tripedalism In: Chen W., Hosoda K., Menegatti E., Shimizu M., Wang H. (eds) Intelligent Autonomous Systems 14. IAS 2016. Advances in Intelligent Systems and Computing, vol 531.2017
Author(s)
Arito Yozu, Dai Owaki, Masashi Hamada, Takuya Sasaki, Qi An, Tetsuro Funato, Nobuhiko Haga
Total Pages
8
Publisher
Springer, Cham
Related Report
